Stearic Acid

Stearic Acid

SCHEMBL2153245

CCCCCCCCCCCCCCCCCC(=O)O.CCN(CC)C(=O)CN

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.61
PPARG P37231 7/20 0.61
PPARD Q03181 7/20 0.61
PPARA Q07869 7/20 0.61
HDAC11 Q96DB2 5/20 0.61
TSHR P16473 4/20 0.61
PTPN1 P18031 3/20 0.61
FABP4 P15090 3/20 0.61
ALDH1A1 P00352 2/20 0.61
TLR2 O60603 2/20 0.61
TDP1 Q9NUW8 2/20 0.61
KMT2A Q03164 2/20 0.61
ALOX15 P16050 2/20 0.61
HSD17B10 Q99714 2/20 0.61
SLC22A6 Q4U2R8 1/20 0.61
SLC22A8 Q8TCC7 1/20 0.61
MEN1 O00255 1/20 0.61
ESR1 P03372 1/20 0.61
PDE4A P27815 1/20 0.61
PDE3A Q14432 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Stearic Acid SCHEMBL16107259 0.88 GPR84 (0.59) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL2153198 0.88 GPR84 (0.59) GPR84PPARGPPARDPPARAHDAC11
Behenic Acid SCHEMBL16107136 0.88 GPR84 (0.59) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL16107206 0.84 GPR84 (0.63) GPR84PPARGPPARDPPARAHDAC11
Octanoic Acid SCHEMBL1031982 0.82 GPR84 (0.81) GPR84PPARGPPARDPPARAHDAC11
Myristic Acid SCHEMBL7533929 0.82 GPR84 (0.81) GPR84PPARGPPARDPPARAHDAC11
Decanoic Acid SCHEMBL31288181 0.82 GPR84 (0.81) GPR84PPARGPPARDPPARAHDAC11
Behenic Acid SCHEMBL30471113 0.82 GPR84 (0.81) GPR84PPARGPPARDPPARAHDAC11
Dodecanoate SCHEMBL28507105 0.82 GPR84 (0.81) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL9164233 0.82 GPR84 (0.81) GPR84PPARGPPARDPPARAHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11351100-B2 Hair coloring agent composition SUNNYPLACE CO., LTD. (JP) 2022-06-07 US claimed
US-20210346267-A1 HAIR COLORING AGENT COMPOSITION SUNNYPLACE CO., LTD. (JP) 2021-11-11 US claimed
WO-2024196194-A1 NOVEL ENTEROCOCCUS FAECALIS HL1 STRAIN AND USE THEREOF 재단법인 아산사회복지재단 2024-09-26 WO disclosed
WO-2024181594-A1 BROCCOLI SPROUT FERMENTATION METHOD TO INCREASE ACTIVE INGREDIENT CONTENT, AND BROCCOLI SPROUT POWDER PRODUCED THEREBY 주식회사 컴투네이처 2024-09-06 WO disclosed
US-20230338425-A1 NOVEL USE OF MILK EXOSOMES KOREA INSTITUTE OF SCIENCE AND TECHOLOGY (KR) 2023-10-26 US disclosed
US-20230338426-A1 NOVEL USE OF MILK EXOSOMES KOREA INSTITUTE OF SCIENCE AND TECHOLOGY (KR) 2023-10-26 US disclosed
US-20230321149-A1 NOVEL USE OF MILK EXOSOMES KOREA INSTITUTE OF SCIENCE AND TECHOLOGY (KR) 2023-10-12 US disclosed
CN-116360028-A Polarizing plate with surface protective film 日东电工株式会社 2023-06-30 CN disclosed
US-20230000920-A1 NOVEL USE OF MILK EXOSOMES KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2023-01-05 US disclosed
EP-4066816-A1 NOVEL USE OF MILK EXOSOMES Korea Institute of Science and Technology (KR) 2022-10-05 EP disclosed
US-11351100-B2 Hair coloring agent composition SUNNYPLACE CO., LTD. (JP) 2022-06-07 US disclosed
EP-2786738-A1 HAIR TREATMENT AGENT COMPOSITION Kao Corporation (JP) 2014-10-08 EP disclosed
US-20140290688-A1 HAIR TREATMENT COMPOSITION KAO CORPORATION (JP) 2014-10-02 US disclosed
US-20130023591-A1 Phenyl-Containing Organopolysiloxane Composition, Raw Cosmetic Material, and Glossy Cosmetic Material DOW CORNING TORAY CO., LTD. (JP) 2013-01-24 US disclosed
EP-2519587-A1 PHENYL-CONTAINING ORGANOPOLYSILOXANE COMPOSITION, RAW COSMETIC MATERIAL, AND GLOSSY COSMETIC MATERIAL Dow Corning Toray Co., Ltd. (JP) 2012-11-07 EP disclosed
WO-2011081218-A1 PHENYL-CONTAINING ORGANOPOLYSILOXANE COMPOSITION, RAW COSMETIC MATERIAL, AND GLOSSY COSMETIC MATERIAL DOW CORNING TORAY CO., LTD. (JP) 2011-07-07 WO disclosed
US-7635465-B2 Reducing agent for straightening curly hair and process for straightening curly hair MILBON CO., LTD. (JP) 2009-12-22 US disclosed
EP-1466582-B1 Hair treatment agent comprising a silylated peptide-silane copolymer SEIWA KASEI CO LTD (JP) 2009-07-29 EP disclosed
US-20060222618-A1 Reducing agent for straightening curly hair and process for straightening curly hair MILBON CO., LTD. (JP) 2006-10-05 US disclosed
EP-1466582-A1 Hair treatment composition comprising a silylated peptide-silane copolymer Seiwa Kasei Company, Limited (JP) 2004-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140290688-A1 HAIR TREATMENT COMPOSITION APOB, PLIN3, AGK GPR84 902/4885PPARG 345/4885PPARD 918/4885
US-20130023591-A1 Phenyl-Containing Organopolysiloxane Composition, Raw Cosmetic Material, and Glossy Cosmetic Material MITF, XPA, FANCI GPR84 701/4885PPARG 2286/4885PPARD 3143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.