Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | MC3R | P41968 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.39 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.39 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isocaffiene SCHEMBL515995 | 0.82 | LMNA (0.57) | ADORA2BLMNAADORA2APOLBPIK3CD | |
| SCHEMBL15086862 | 0.75 | LMNA (0.40) | ADORA2BLMNAADORA2APOLBPIK3CD | |
| SCHEMBL22471375 | 0.75 | PDE4A (0.49) | ADORA2BLMNAADORA2APDE4APDE4B | |
| SCHEMBL23974902 | 0.73 | LMNA (0.39) | ADORA2BLMNAADORA2APOLBPIK3CD | |
| SCHEMBL10958621 | 0.72 | ADORA2B (0.69) | ADORA2BLMNAADORA2APOLBPIK3CD | |
| SCHEMBL23974900 | 0.71 | ADORA3 (0.52) | ADORA2BPOLBADORA3ALDH1A1CYP3A4 | |
| SCHEMBL13111707 | 0.71 | PDE1A (0.49) | LMNAADORA2AADORA1ALDH1A1PDE4A | |
| SCHEMBL23473311 | 0.71 | LMNA (0.40) | ADORA2BLMNAADORA2APOLBPIK3CD | |
| SCHEMBL13153172 | 0.70 | CYP3A4 (0.41) | ADORA2BLMNAADORA2APOLBGDA | |
| SCHEMBL23974894 | 0.68 | LMNA (0.38) | ADORA2BLMNAADORA2AALDH1A1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10464960-B2 | Salen complexes with dianionic counterions | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2019-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10464960-B2 | Salen complexes with dianionic counterions | NCLN, POLN, NCL | ADORA2B 3680/4885LMNA 938/4885ADORA2A 3937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.