Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | ALDH1A2 | O94788 | 3/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | USP1 | O94782 | 1/20 | 0.33 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21536162 | 0.81 | KDM4E (0.39) | ALDH1A1ALDH1A2ALDH1A3TSHRKDM4E | |
| SCHEMBL21536089 | 0.77 | ALDH1A2 (0.39) | ALDH1A1ALDH1A2ALDH1A3USP1WDR48 | |
| SCHEMBL24837078 | 0.72 | ALDH1A2 (0.33) | ALDH1A1ALDH1A2ALDH1A3USP1WDR48 | |
| SCHEMBL18368379 | 0.72 | LMNA (0.39) | ALDH1A1CYP1A2CYP3A4HPGDTSHR | |
| SCHEMBL27107103 | 0.70 | USP1 (0.33) | ALDH1A1ALDH1A2ALDH1A3USP1WDR48 | |
| SCHEMBL29303756 | 0.70 | KDM5A (0.38) | ALDH1A1ALDH1A2ALDH1A3HPGDKDM4E | |
| SCHEMBL24370960 | 0.70 | LMNA (0.38) | ALDH1A1CYP1A2CYP3A4HPGDTSHR | |
| SCHEMBL26142046 | 0.69 | MTOR (0.34) | ALDH1A1ALDH1A2ALDH1A3USP1WDR48 | |
| SCHEMBL22358041 | 0.69 | ALDH1A1 (0.36) | ALDH1A1ALDH1A2ALDH1A3HPGDKDM4E | |
| SCHEMBL21536093 | 0.69 | USP1 (0.37) | CYP1A2USP1WDR48MAPK1CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10919885-B2 | Compounds and uses thereof | YUMANITY THERAPEUTICS, INC. (US) | 2021-02-16 | — | — | US | disclosed |
| US-20190330198-A1 | COMPOUNDS AND USES THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2019-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10919885-B2 | Compounds and uses thereof | NLN, ACHE, CLN6 | ALDH1A1 656/4885ALDH1A2 138/4885ALDH1A3 379/4885 |
| US-20190330198-A1 | COMPOUNDS AND USES THEREOF | NLN, ACHE, CLN6 | ALDH1A1 656/4885ALDH1A2 138/4885ALDH1A3 379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.