Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16276160 | 0.80 | FAAH (0.39) | — | |
| SCHEMBL10060469 | 0.80 | ALDH1A1 (0.30) | TDP1 | |
| SCHEMBL13542695 | 0.75 | MEN1 (0.37) | TDP1 | |
| SCHEMBL7195371 | 0.74 | TDP1 (0.40) | TDP1 | |
| SCHEMBL23696048 | 0.73 | MEN1 (0.40) | TDP1 | |
| SCHEMBL12600744 | 0.73 | — | — | |
| SCHEMBL22856475 | 0.73 | MEN1 (0.40) | TDP1 | |
| SCHEMBL10165857 | 0.73 | — | — | |
| SCHEMBL23696339 | 0.73 | MEN1 (0.40) | TDP1 | |
| SCHEMBL21564105 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10464941-B2 | Therapeutic compounds | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2019-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10464941-B2 | Therapeutic compounds | SDHA, CYP11B2, SDHB | TDP1 2697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.