Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21552709 | 0.98 | L3MBTL1 (0.51) | GAAL3MBTL1NAAAALDH1A1KMT2A | |
| Potassium Ion SCHEMBL21544694 | 0.82 | NAAA (0.49) | GAAL3MBTL1NAAAALDH1A1KMT2A | |
| SCHEMBL2074046 | 0.82 | GAA (0.64) | GAAL3MBTL1NAAAALDH1A1KMT2A | |
| SCHEMBL21544662 | 0.78 | ALDH1A1 (0.53) | GAANAAAALDH1A1KMT2AMEN1 | |
| SCHEMBL26089332 | 0.78 | L3MBTL1 (0.48) | GAAL3MBTL1NAAAALDH1A1KMT2A | |
| SCHEMBL28731178 | 0.77 | HTR3E (0.52) | GAAL3MBTL1NAAAALDH1A1KMT2A | |
| SCHEMBL17027050 | 0.76 | NOTUM (0.72) | ALDH1A1KMT2ANOTUMMEN1 | |
| SCHEMBL16695293 | 0.75 | NOTUM (0.75) | ALDH1A1AKR1C3NOTUMMAPTSMN1; SMN2 | |
| SCHEMBL22804834 | 0.75 | NOTUM (0.51) | ALDH1A1KMT2AAKR1C3NOTUMCES2 | |
| SCHEMBL6270203 | 0.75 | HTT (0.63) | GAAALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10689357-B2 | N-acylethanolamine hydrolyzing acid amidase (NAAA) inhibitors and use thereof | NORTHEASTERN UNIVERSITY (US) | 2020-06-23 | — | — | US | disclosed |
| US-20190345132-A1 | N-Acylethanolamine Hydrolyzing Acid Amidase (NAAA) Inhibitors And Use Thereof | NORTHEASTERN UNIVERSITY | 2019-11-14 | — | — | US | disclosed |
| WO-2019217977-A1 | N-ACYLETHANOLAMINE HYDROLYZING ACID AMIDASE (NAAA) INHIBITORS AND USE THEREOF | NORTHEASTERN UNIVERSITY (US) | 2019-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10689357-B2 | N-acylethanolamine hydrolyzing acid amidase (NAAA) inhibitors and use thereof | NAAA, NAT1, ACHE | GAA 186/4885L3MBTL1 4352/4885NAAA 1/4885 |
| US-20190345132-A1 | N-Acylethanolamine Hydrolyzing Acid Amidase (NAAA) Inhibitors And Use Thereof | NAAA, NAT1, ACHE | GAA 186/4885L3MBTL1 4352/4885NAAA 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.