Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1865361 | 0.81 | GABRA1 (0.48) | GABRA1GABRB2CYP3A4MAPTAKR1B1 | |
| SCHEMBL8977878 | 0.80 | ALDH1A1 (0.47) | PTGDRPTGDR2CYP3A4TP53MAPT | |
| SCHEMBL9399710 | 0.79 | GABRA1 (0.38) | GABRA1GABRB2CYP3A4MAPTPOLB | |
| Methane SCHEMBL28151881 | 0.79 | GABRA1 (0.47) | GABRA1GABRB2CYP3A4MAPTAKR1B1 | |
| SCHEMBL2162708 | 0.79 | XDH (0.39) | GABRA1GABRB2CYP3A4TP53MAPT | |
| SCHEMBL9721939 | 0.77 | GABRA1 (0.45) | GABRA1GABRB2MAPTKDM4EAKR1B1 | |
| SCHEMBL467130 | 0.77 | DHFR (0.39) | GABRA1GABRB2CYP3A4MAPTKDM4E | |
| SCHEMBL20681220 | 0.77 | GABRA1 (0.36) | GABRA1GABRB2CYP3A4POLBALDH1A1 | |
| SCHEMBL10410485 | 0.77 | GABRA1 (0.36) | GABRA1GABRB2MAPTLMNAPOLB | |
| SCHEMBL9399475 | 0.77 | GABRA1 (0.36) | GABRA1GABRB2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4401833-A | Process for the preparation of 4-chloro-2,6-dialkylanilines | BAYER AKTIENGESELLSCHAFT (DE) | 1983-08-30 | — | — | US | claimed |
| US-9193667-B2 | Process for the selective meta-chlorination of alkylanilines | LONZA LTD. (CH) | 2015-11-24 | — | — | US | disclosed |
| US-20130338400-A1 | PROCESS FOR THE SELECTIVE META-CHLORINATION OF ALKYLANILINES | LONZA LTD. (CH) | 2013-12-19 | — | — | US | disclosed |
| EP-2606028-A1 | PROCESS FOR THE SELECTIVE META-CHLORINATION OF ALKYLANILINES | Lonza Ltd (CH) | 2013-06-26 | — | — | EP | disclosed |
| WO-2012022460-A1 | PROCESS FOR THE SELECTIVE META-CHLORINATION OF ALKYLANILINES | LONZA LTD (CH) | 2012-02-23 | — | — | WO | disclosed |
| US-4401833-A | Process for the preparation of 4-chloro-2,6-dialkylanilines | BAYER AKTIENGESELLSCHAFT (DE) | 1983-08-30 | — | — | US | disclosed |
| US-4401833-A | Process for the preparation of 4-chloro-2,6-dialkylanilines | BAYER AKTIENGESELLSCHAFT (DE) | 1983-08-30 | — | — | US | disclosed |
| US-4401833-A | Process for the preparation of 4-chloro-2,6-dialkylanilines | BAYER AKTIENGESELLSCHAFT (DE) | 1983-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130338400-A1 | PROCESS FOR THE SELECTIVE META-CHLORINATION OF ALKYLANILINES | CLIC4, CLIC1, NPM1 | PTGDR 4154/4885PTGDR2 4441/4885GABRA1 644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.