Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 8/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.32 |
| ▸ | PDCD1LG2 | Q9BQ51 | 4/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21548857 | 0.89 | KMT2A (0.34) | CD274PDCD1LG2MEN1ALDH1A1KMT2A | |
| SCHEMBL21526060 | 0.83 | CCR4 (0.35) | CCR4KDM4ECD274PDCD1ALDH1A1 | |
| SCHEMBL21548877 | 0.81 | ALDH1A1 (0.43) | CD274PDCD1LG2PKMALDH1A1KMT2A | |
| SCHEMBL21548814 | 0.76 | LMNA (0.39) | KDM4EMEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL21548886 | 0.75 | GRM4 (0.35) | CCR4MEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL21548888 | 0.74 | SMN1; SMN2 (0.41) | CCR4KDM4EALDH1A1PIK3CDPIK3CA | |
| SCHEMBL20356755 | 0.73 | CCR4 (0.38) | CCR4CD274PDCD1LG2MEN1MAPT | |
| SCHEMBL20356522 | 0.73 | ALDH1A1 (0.38) | KDM4ECD274PDCD1LG2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL21526057 | 0.72 | ALDH1A1 (0.37) | KDM4EALDH1A1MAPTKMT2AL3MBTL1 | |
| SCHEMBL21548847 | 0.70 | KDM4E (0.42) | KDM4EMEN1ALDH1A1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3564216-B1 | PYRIMIDINE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2021-10-27 | — | — | EP | disclosed |
| EP-3564216-A1 | PYRIMIDINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2019-11-06 | — | — | EP | disclosed |