Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21548940 | 0.89 | CCR4 (0.35) | KMT2AALDH1A1L3MBTL1PDCD1LG2CD274 | |
| SCHEMBL21548814 | 0.88 | LMNA (0.39) | KMT2AALDH1A1L3MBTL1LMNAMEN1 | |
| SCHEMBL21548886 | 0.86 | GRM4 (0.35) | KMT2AALDH1A1ATML3MBTL1MEN1 | |
| SCHEMBL20356522 | 0.83 | ALDH1A1 (0.38) | KMT2AALDH1A1ATML3MBTL1PDCD1LG2 | |
| Hydrochloric Acid SCHEMBL21526057 | 0.82 | ALDH1A1 (0.37) | KMT2AALDH1A1ATML3MBTL1LMNA | |
| SCHEMBL21548856 | 0.79 | HTT (0.40) | KMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL21526068 | 0.75 | PTPN11 (0.36) | KMT2AALDH1A1ATML3MBTL1PDCD1LG2 | |
| SCHEMBL21526043 | 0.74 | GAA (0.39) | KMT2AALDH1A1ATML3MBTL1MEN1 | |
| SCHEMBL21526060 | 0.73 | CCR4 (0.35) | ALDH1A1CD274 | |
| SCHEMBL21526129 | 0.72 | GAA (0.33) | KMT2AALDH1A1ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3564216-B1 | PYRIMIDINE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2021-10-27 | — | — | EP | disclosed |
| EP-3564216-A1 | PYRIMIDINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2019-11-06 | — | — | EP | disclosed |