Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21548857 | 0.88 | KMT2A (0.34) | LMNAL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL21548886 | 0.83 | GRM4 (0.35) | L3MBTL1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL21526086 | 0.81 | LMNA (0.42) | LMNAL3MBTL1ALDH1A1NPC1HTT | |
| SCHEMBL21548856 | 0.78 | HTT (0.40) | LMNAALDH1A1NPC1HTTRAB9A | |
| SCHEMBL21548940 | 0.76 | CCR4 (0.35) | LMNAL3MBTL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL20356522 | 0.71 | ALDH1A1 (0.38) | LMNAL3MBTL1ALDH1A1SLC26A6KDM4E | |
| SCHEMBL21548877 | 0.71 | ALDH1A1 (0.43) | ALDH1A1HTTKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL21526057 | 0.70 | ALDH1A1 (0.37) | LMNAL3MBTL1ALDH1A1SLC26A6KDM4E | |
| SCHEMBL21548847 | 0.70 | KDM4E (0.42) | L3MBTL1ALDH1A1RAB9ASLC26A6KDM4E | |
| SCHEMBL20356519 | 0.67 | MAPK8 (0.38) | LMNAL3MBTL1ALDH1A1NPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3564216-B1 | PYRIMIDINE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2021-10-27 | — | — | EP | disclosed |
| EP-3564216-A1 | PYRIMIDINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2019-11-06 | — | — | EP | disclosed |