Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11706225 | 0.86 | POLB (0.57) | MTNR1AMTNR1BALDH1A1KDM4EMAPT | |
| SCHEMBL8772666 | 0.82 | MTNR1A (0.57) | MTNR1AMTNR1BGAAALDH1A1KDM4E | |
| SCHEMBL4081034 | 0.80 | MTNR1A (0.55) | MTNR1AMTNR1BGAAALDH1A1KDM4E | |
| SCHEMBL22284793 | 0.79 | GAA (0.50) | MTNR1AMTNR1BGAAALDH1A1KDM4E | |
| SCHEMBL51653 | 0.79 | GAA (0.53) | MTNR1AMTNR1BGAAALDH1A1KDM4E | |
| SCHEMBL13186651 | 0.79 | APLNR (0.56) | MTNR1AMTNR1BALDH1A1MEN1MAPT | |
| SCHEMBL6035932 | 0.79 | HSD17B10 (0.70) | MTNR1AMTNR1BGAAALDH1A1KDM4E | |
| SCHEMBL4034916 | 0.77 | MTNR1A (0.56) | MTNR1AMTNR1BGAAALDH1A1KDM4E | |
| SCHEMBL24187388 | 0.77 | ALDH1A1 (0.49) | GAAALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL805304 | 0.77 | MTNR1A (0.55) | MTNR1AMTNR1BGAAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019214749-A1 | METHOD FOR SYNTHESIZING BENZOFURAN DERIVATIVE BY MEANS OF NON-METAL LEWIS ACID CATALYZING ADDITION OF C-O BOND WITHIN OLEFIN MOLECULE | 南京晓庄学院 (CN) | 2019-11-14 | — | — | WO | disclosed |