SCHEMBL805304

SCHEMBL805304

CCc1cc(OC)ccc1O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 1/20 0.55
MTNR1B P49286 1/20 0.55
ERN1 O75460 1/20 0.53
CA1 P00915 4/20 0.53
CA2 P00918 4/20 0.53
GAA P10253 2/20 0.52
ALDH1A1 P00352 2/20 0.52
KDM4E B2RXH2 1/20 0.52
MEN1 O00255 1/20 0.52
MAPT P10636 1/20 0.52
THRB P10828 1/20 0.52
RECQL P46063 1/20 0.52
BLM P54132 1/20 0.52
KMT2A Q03164 1/20 0.52
MCL1 Q07820 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
HSP90AA1 P07900 1/20 0.51
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL51653 0.85 GAA (0.53) MTNR1AMTNR1BERN1CA1CA2
SCHEMBL921473 0.85 ESR1 (0.52) MTNR1AMTNR1BMEN1MAPTTHRB
SCHEMBL10366349 0.84 MTNR1A (0.56) MTNR1AMTNR1BERN1CA1CA2
SCHEMBL2045876 0.83 POLB (0.64) ERN1ALDH1A1MAPTKMT2AHSP90AA1
SCHEMBL1638977 0.83 GAA (0.52) MTNR1AMTNR1BERN1CA1CA2
SCHEMBL4081034 0.82 MTNR1A (0.55) MTNR1AMTNR1BERN1CA1CA2
SCHEMBL14451135 0.82 CA1 (0.56) CA1CA2ALDH1A1MAPTKMT2A
SCHEMBL9660984 0.82 CA1 (0.51) MTNR1AMTNR1BCA1CA2GAA
SCHEMBL21248098 0.82 ALDH1A1 (0.50) MTNR1AMTNR1BERN1CA1CA2
SCHEMBL22284793 0.82 GAA (0.50) MTNR1AMTNR1BERN1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114702372-B Method for preparing 4- (2-methoxyl) ethylphenol 台州市前进化工有限公司 2022-12-16 CN claimed
CN-111018724-B Metoprolol and preparation method thereof 江西美晶科技有限公司 2022-11-08 CN claimed
CN-114702372-A Method for preparing high-purity 4- (2-methoxy) ethylphenol 台州市前进化工有限公司 2022-07-05 CN claimed
CN-109651094-B Preparation method of p- (2-methoxy) ethylphenol 浙江永太科技股份有限公司 2021-09-28 CN claimed
CN-111116328-A Preparation method of metoprolol intermediate 江西美晶科技有限公司 2020-05-08 CN claimed
CN-111018724-A Metoprolol and preparation method thereof 江西美晶科技有限公司 2020-04-17 CN claimed
CN-210115064-U P- (2-methoxy) ethyl phenol methylation reaction kettle 江西美晶科技有限公司 2020-02-28 CN claimed
US-12583813-B2 Polymerization inhibitors BASF SE (DE) 2026-03-24 US disclosed
US-20230242472-A1 POLYMERIZATION INHIBITORS BASF SE (DE) 2023-08-03 US disclosed
CN-114956978-B Microwave synthesis process of 2-hydroxy-5-methoxy acetophenone 重庆康普化学工业股份有限公司 2023-06-27 CN disclosed
CN-116261399-A Citrus oil extract 弗门尼舍有限公司 2023-06-13 CN disclosed
US-20230159421-A1 SUBSTITUTED HYDROXYSTILBENE COMPOUNDS AND DERIVATIVES SYNTHESIS AND USES THEREOF Kynan Duke IP, LLC (US) 2023-05-25 US disclosed
CN-116020438-A Solid acid catalyst, preparation method thereof and application of solid acid catalyst in deprotection reaction of p-tert-butoxyphenethyl methyl ether 山东普洛汉兴医药有限公司 2023-04-28 CN disclosed
US-4783462-A 3(2H)pyridazinone, and anti-allergic agent containing it NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1988-11-08 US disclosed
US-4631252-A PHOTOGRAPHIC STABILIZERS CIBA-GEIGY AG (CH) 1986-12-23 US disclosed
US-4616082-A PHOTOGRAPHIC STABILIZERS CIBA-GEIGY AG (CH) 1986-10-07 US disclosed
EP-0193853-A2 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1986-09-10 EP disclosed
US-4549015-A PHOTOHRAPHIC STABILIZERS CIBA-GEIGY AG (CH) 1985-10-22 US disclosed
EP-0098241-B1 HYDROQUINONE ETHERS AND A PROCESS FOR PREPARING THEM CIBA-GEIGY AG (CH) 1985-10-02 EP disclosed
EP-0098241-A1 Hydroquinone ethers and a process for preparing them CIBA-GEIGY AG (CH) 1984-01-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242472-A1 POLYMERIZATION INHIBITORS RCE1, CABLES1, DPYD MTNR1A 3939/4885MTNR1B 4085/4885ERN1 1551/4885
US-12583813-B2 Polymerization inhibitors PTGS1, PTGER1, POT1 MTNR1A 3620/4885MTNR1B 3999/4885ERN1 868/4885
US-20230159421-A1 SUBSTITUTED HYDROXYSTILBENE COMPOUNDS AND DERIVATIVES SYNTHESIS AND USES THEREOF CYP8B1, HSD11B1, HSD11B2 MTNR1A 1856/4885MTNR1B 563/4885ERN1 2632/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.