SCHEMBL21550136 — predicted protein targets

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	LPL	P06858	5/20	0.34

▸	LIPG	Q9Y5X9	5/20	0.34

▸	ESR2	Q92731	1/20	0.34

▸	F11	P03951	1/20	0.33

▸	ANPEP	P15144	1/20	0.33

▸	LAP3	P28838	1/20	0.33

▸	UCHL1	P09936	1/20	0.31

▸	HIF1A	Q16665	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL16971348	0.79	LPL (0.45)	LPLLIPGESR2F11ANPEP
SCHEMBL16971971	0.79	LPL (0.45)	LPLLIPGESR2F11ANPEP
SCHEMBL20157282	0.74	LIPG (0.37)	LPLLIPGESR2F11UCHL1
SCHEMBL20157773	0.73	F11 (0.40)	LPLLIPGESR2F11ANPEP
SCHEMBL21550138	0.72	LPL (0.39)	LPLLIPGESR2F11UCHL1
SCHEMBL21550113	0.72	CA12 (0.36)	HIF1A
SCHEMBL16972228	0.70	ALDH1A1 (0.42)	LPLLIPGESR2F11ANPEP
SCHEMBL16971653	0.70	ALDH1A1 (0.42)	LPLLIPGESR2F11ANPEP
SCHEMBL28601719	0.69	LPL (0.36)	LPLLIPGF11
SCHEMBL24252766	0.68	LPL (0.47)	LPLLIPGESR2F11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2019214399-A1	BENZO- SEVEN-MEMBERED HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION THEREOF	罗欣药业(上海)有限公司 (CN)	2019-11-14	—	—	WO	disclosed