SCHEMBL2155189

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2155611	0.86	CHRNB2 (0.43)	SMN1; SMN2TSHRRAB9AALDH1A1HPGD
	SCHEMBL2155051	0.85	SMN1; SMN2 (0.44)	SMN1; SMN2TSHRRAB9AALDH1A1HPGD
	SCHEMBL14359121	0.84	ALDH1A1 (0.47)	SMN1; SMN2TSHRRAB9AALDH1A1HPGD
	SCHEMBL14716747	0.82	CYP1A2 (0.56)	SMN1; SMN2TSHRRAB9AALDH1A1HPGD
	SCHEMBL16183994	0.78	ALDH1A1 (0.44)	SMN1; SMN2TSHRALDH1A1HPGDNPC1
	SCHEMBL16183310	0.77	KMT2A (0.52)	TSHRALDH1A1HPGDNPC1POLB
	SCHEMBL14474390	0.77	ABCG2 (0.51)	TSHRRAB9AALDH1A1HPGDL3MBTL1
	SCHEMBL16184162	0.77	KMT2A (0.46)	SMN1; SMN2TSHRRAB9AALDH1A1HPGD
	Hydrochloric Acid SCHEMBL7280022	0.76	PDE5A (0.52)	TSHRALDH1A1HPGDNPC1POLB
	SCHEMBL2162585	0.75	CYP11B1 (0.49)	SMN1; SMN2TSHRALDH1A1HPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.