Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | MAOA | P21397 | 1/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.66 |
| ▸ | HCAR2 | Q8TDS4 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15445002 | 0.84 | CYP1A2 (0.68) | CYP1A2KDM4ELMNASMN1; SMN2NPC1 | |
| SCHEMBL29921611 | 0.84 | HCAR2 (0.57) | CYP1A2HCAR2 | |
| SCHEMBL151952 | 0.84 | HCAR2 (0.57) | CYP1A2HCAR2 | |
| SCHEMBL5236795 | 0.84 | CYP1A2 (0.68) | CYP1A2KDM4ELMNASMN1; SMN2NPC1 | |
| SCHEMBL4548489 | 0.82 | HCAR2 (0.52) | CYP1A2KDM4ELMNASMN1; SMN2NPC1 | |
| SCHEMBL20323255 | 0.82 | CYP1A2 (0.66) | CYP1A2KDM4ELMNASMN1; SMN2NPC1 | |
| SCHEMBL5692811 | 0.81 | ALOX5 (0.51) | CYP1A2KDM4ELMNASMN1; SMN2NPC1 | |
| SCHEMBL4548368 | 0.81 | LMNA (0.53) | CYP1A2KDM4ELMNASMN1; SMN2NPC1 | |
| SCHEMBL2615110 | 0.81 | CYP1A2 (0.64) | CYP1A2KDM4ELMNASMN1; SMN2NPC1 | |
| Raspberryketone SCHEMBL43308 | 0.81 | ALDH1A1 (0.65) | CYP1A2KDM4ELMNASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10471025-B2 | Compositions for use in treating parkinson's disease and related disorders | TECHNOPHAGE, INVESTIGACAO E DESENVOLVIMENTO EM BIOTECNOLOGIA, SA | 2019-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10471025-B2 | Compositions for use in treating parkinson's disease and related disorders | PARK7, SLC6A3, SNCA | CYP1A2 3734/4885KDM4E 2147/4885LMNA 2600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.