SCHEMBL215575

SCHEMBL215575

CCN(CC)c1ccc(C(=NO[Si](c2ccccc2)(c2ccccc2)c2ccccc2)c2ccc(N(CC)CC)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.41
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
NOX1 Q9Y5S8 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
HDAC6 Q9UBN7 1/20 0.40
MAPT P10636 4/20 0.40
LMNA P02545 2/20 0.40
CNR2 P34972 2/20 0.40
ALDH1A1 P00352 4/20 0.39
HPGD P15428 2/20 0.39
ESRRG P62508 1/20 0.39
HSD17B10 Q99714 1/20 0.39
GAA P10253 3/20 0.36
KDM4E B2RXH2 2/20 0.36
GFER P55789 1/20 0.36
KDM1A O60341 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL216485 0.83 ALDH1A1 (0.41) HSD11B1MEN1KMT2ANPC1RAB9A
SCHEMBL214936 0.82 CNR2 (0.45) HSD11B1MEN1KMT2ANPC1RAB9A
SCHEMBL213953 0.79 ALDH1A1 (0.40) KMT2AMAPTLMNAALDH1A1HPGD
SCHEMBL216089 0.75 MAPT (0.46) HSD11B1MEN1KMT2ANOX1TDP1
SCHEMBL214985 0.74 ALDH1A1 (0.50) MEN1KMT2ANPC1RAB9ATDP1
SCHEMBL214986 0.74 ALDH1A1 (0.50) MEN1KMT2ANPC1RAB9ATDP1
SCHEMBL214129 0.72 HSD11B1 (0.54) HSD11B1MEN1KMT2ANPC1RAB9A
SCHEMBL213048 0.71 ALDH1A1 (0.41) HSD11B1MEN1KMT2ANOX1TDP1
SCHEMBL17257004 0.71 SMN1; SMN2 (0.43) MEN1KMT2ANPC1RAB9AMAPT
SCHEMBL214657 0.70 MAPT (0.49) HSD11B1MEN1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088868-B2 oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis BRIDGESTONE CORPORATION (JP) 2012-01-03 US claimed
US-20080146745-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2008-06-19 US claimed
US-8088868-B2 oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis BRIDGESTONE CORPORATION (JP) 2012-01-03 US disclosed
US-20080146745-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2008-06-19 US disclosed