SCHEMBL214936

SCHEMBL214936

CCN(CC)c1ccc(C(=NO[Si](Cc2ccccc2)(Cc2ccccc2)Cc2ccccc2)c2ccc(N(CC)CC)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 4/20 0.45
TSHR P16473 1/20 0.41
HSD11B1 P28845 1/20 0.40
KMT2A Q03164 4/20 0.40
MAPT P10636 4/20 0.40
ALDH1A1 P00352 3/20 0.40
HPGD P15428 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
NOX1 Q9Y5S8 2/20 0.40
LMNA P02545 2/20 0.40
KDM4E B2RXH2 2/20 0.40
MITF O75030 1/20 0.40
MAPK1 P28482 1/20 0.40
RAD52 P43351 1/20 0.40
HDAC6 Q9UBN7 1/20 0.39
MEN1 O00255 3/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
PPARG P37231 1/20 0.39
ESRRG P62508 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL215575 0.82 HSD11B1 (0.41) CNR2TSHRHSD11B1KMT2AMAPT
SCHEMBL216485 0.79 ALDH1A1 (0.41) TSHRHSD11B1KMT2AMAPTALDH1A1
SCHEMBL213227 0.77 ALDH1A1 (0.50) CNR2TSHRKMT2AMAPTALDH1A1
SCHEMBL213228 0.77 ALDH1A1 (0.50) CNR2TSHRKMT2AMAPTALDH1A1
SCHEMBL216089 0.74 MAPT (0.46) TSHRHSD11B1KMT2AMAPTALDH1A1
SCHEMBL214062 0.72 NOS2 (0.40) TSHRMAPTALDH1A1TDP1LMNA
SCHEMBL214657 0.72 MAPT (0.49) TSHRHSD11B1KMT2AMAPTALDH1A1
SCHEMBL214129 0.71 HSD11B1 (0.54) CNR2HSD11B1KMT2AMAPTALDH1A1
SCHEMBL214457 0.71 LMNA (0.53) MAPTALDH1A1HPGDTDP1LMNA
SCHEMBL214915 0.71 NOS2 (0.37) KMT2AALDH1A1TDP1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088868-B2 oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis BRIDGESTONE CORPORATION (JP) 2012-01-03 US claimed
US-20080146745-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2008-06-19 US claimed
US-8088868-B2 oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis BRIDGESTONE CORPORATION (JP) 2012-01-03 US disclosed
US-20080146745-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2008-06-19 US disclosed