Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 10/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 8/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 8/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 8/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2156342 | 0.84 | SGMS2 (0.35) | ERN1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL2990746 | 0.78 | ALDH1A1 (0.34) | ARKDM4EPOLB | |
| SCHEMBL2156683 | 0.74 | PLA2G1B (0.38) | ARKDM4EMEN1POLBKMT2A | |
| SCHEMBL2982702 | 0.71 | KDM4E (0.39) | ARKDM4EKMT2ATDP1 | |
| SCHEMBL425802 | 0.68 | PTGER1 (0.47) | PTGER1PTGER4PTGER3PTGER2RXRA | |
| SCHEMBL428409 | 0.67 | PTGER1 (0.41) | PTGER1PTGER4PTGER3PTGER2RXRA | |
| SCHEMBL2990743 | 0.64 | SLC6A9 (0.33) | — | |
| SCHEMBL3001810 | 0.64 | ACHE (0.38) | — | |
| SCHEMBL2987823 | 0.64 | SLC6A3 (0.34) | KDM4EMEN1KMT2A | |
| SCHEMBL15471999 | 0.62 | MAPT (0.46) | KDM4EMEN1POLBKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973026-B2 | Thienopyrroles as antiviral agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2011-07-05 | — | — | US | disclosed |
| US-20090105227-A1 | Thienopyrroles As Antiviral Agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105227-A1 | Thienopyrroles As Antiviral Agents | ZC3HAV1, HAVCR2, ZC3HAV1L | ERN1 2201/4885PTGER1 610/4885PTGER4 899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.