Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.60 |
| ▸ | CDK4 | P11802 | 1/20 | 0.59 |
| ▸ | CCND1 | P24385 | 1/20 | 0.59 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.52 |
| ▸ | USP2 | O75604 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334188 | 0.88 | TRPV1 (0.65) | IDO1CDK4CCND1TRPV1FAAH | |
| SCHEMBL8869454 | 0.86 | LTA4H (0.57) | IDO1GAAHPGDCYP1A2CYP3A4 | |
| SCHEMBL20267062 | 0.85 | CDK4 (0.66) | CDK4CCND1NR4A2GAAHPGD | |
| SCHEMBL7307246 | 0.83 | FAAH (0.56) | HPGDCYP1A2CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL3900495 | 0.82 | IDO1 (0.53) | IDO1GAAHPGDCYP1A2CYP3A4 | |
| SCHEMBL7315015 | 0.82 | TRPV1 (0.57) | IDO1CDK4CCND1MEN1KMT2A | |
| SCHEMBL3891002 | 0.80 | IDO1 (0.53) | IDO1CDK4CCND1GAACYP1A2 | |
| SCHEMBL8613795 | 0.79 | TRPV1 (0.55) | IDO1HPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL798165 | 0.79 | TRPV1 (0.70) | IDO1HPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31077788 | 0.79 | TRPV1 (0.70) | IDO1HPGDCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787783-B2 | Heparanase inhibitors and use thereof | Beta Therapeutics Pty Ltd (AU) | 2023-10-17 | — | — | US | disclosed |
| US-11787783-B2 | Heparanase inhibitors and use thereof | Beta Therapeutics Pty Ltd (AU) | 2023-10-17 | — | — | US | disclosed |
| US-20190345143-A1 | HEPARANASE INHIBITORS AND USE THEREOF | Beta Therapeutics Pty Ltd (AU) | 2019-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190345143-A1 | HEPARANASE INHIBITORS AND USE THEREOF | HPSE, HEXD, ENGASE | IDO1 985/4885CDK4 2267/4885CCND1 4779/4885 |
| US-11787783-B2 | Heparanase inhibitors and use thereof | HPSE, HEXD, ENGASE | IDO1 985/4885CDK4 2267/4885CCND1 4779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.