Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.56 |
| ▸ | LTA4H | P09960 | 3/20 | 0.54 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.54 |
| ▸ | NQO2 | P16083 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334188 | 0.91 | TRPV1 (0.65) | FAAHTRPV1LTA4HPLA2G2AMTNR1A | |
| SCHEMBL7315015 | 0.86 | TRPV1 (0.57) | FAAHTRPV1LTA4HPLA2G2AMEN1 | |
| SCHEMBL21564239 | 0.83 | IDO1 (0.60) | FAAHTRPV1LTA4HPLA2G2AMEN1 | |
| SCHEMBL5745010 | 0.82 | MEN1 (0.67) | FAAHMEN1KMT2AMTNR1ACYP1A2 | |
| SCHEMBL6927448 | 0.82 | MTNR1A (0.74) | FAAHTRPV1NQO2MEN1KMT2A | |
| SCHEMBL8613795 | 0.82 | TRPV1 (0.55) | FAAHTRPV1NQO2MEN1KMT2A | |
| SCHEMBL798165 | 0.82 | TRPV1 (0.70) | TRPV1NQO2MEN1KMT2AKDM4E | |
| SCHEMBL31077788 | 0.82 | TRPV1 (0.70) | TRPV1NQO2MEN1KMT2AKDM4E | |
| SCHEMBL7318352 | 0.81 | MTNR1A (0.70) | FAAHTRPV1NQO2MEN1KMT2A | |
| SCHEMBL2544150 | 0.81 | HPGD (0.55) | FAAHTRPV1NQO2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020004198-A1 | Novel anti-infectives | SMITHKLINE BEECHAM CORPORATION | 2002-01-10 | — | — | US | disclosed |
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION | 2001-07-12 | — | — | US | disclosed |
| WO-2001034146-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | CTSL, MMP8, SERPINB1 | FAAH 3191/4885TRPV1 2884/4885LTA4H 396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.