Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21550051 | 0.89 | ALDH1A1 (0.38) | LMNATP53HTTTOP2ATOP2B | |
| SCHEMBL20157925 | 0.84 | ALDH1A1 (0.36) | LMNATP53ALDH1A1MAPT | |
| SCHEMBL21549993 | 0.84 | OPRM1 (0.38) | HTTMAPTRAB9A | |
| SCHEMBL21564741 | 0.79 | ABL1 (0.33) | LMNASMN1; SMN2NPSR1 | |
| SCHEMBL21550102 | 0.79 | NPC1 (0.39) | MAPTRAB9AKMT2ASLC6A4KCNH2 | |
| SCHEMBL21564749 | 0.78 | CYP1A2 (0.41) | LMNAMEN1ALDH1A1RAB9AKMT2A | |
| SCHEMBL21550094 | 0.77 | SMN1; SMN2 (0.33) | LMNAHTTMEN1ALDH1A1MAPT | |
| SCHEMBL21564854 | 0.77 | LMNA (0.34) | LMNATOP2ATOP2BMEN1MAPT | |
| SCHEMBL21550077 | 0.76 | TRPA1 (0.33) | LMNAMEN1ALDH1A1MAPTRAB9A | |
| SCHEMBL20158035 | 0.75 | ABL1 (0.36) | LMNAMEN1ALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019214399-A1 | BENZO- SEVEN-MEMBERED HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION THEREOF | 罗欣药业(上海)有限公司 (CN) | 2019-11-14 | — | — | WO | disclosed |