Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3440571 | 0.81 | ADAMTS4 (0.35) | CHRM1CHRM3 | |
| SCHEMBL3440572 | 0.81 | ADAMTS4 (0.35) | CHRM1CHRM3 | |
| SCHEMBL14625507 | 0.79 | CHRNB2 (0.31) | — | |
| SCHEMBL19292871 | 0.79 | CHRNB2 (0.31) | — | |
| SCHEMBL13747377 | 0.78 | FDPS (0.36) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL8919611 | 0.78 | FDPS (0.36) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL27259972 | 0.77 | ALDH1A1 (0.31) | CHRM2 | |
| SCHEMBL25662334 | 0.77 | — | — | |
| SCHEMBL21229682 | 0.77 | — | — | |
| SCHEMBL7766013 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019217457-A1 | METHODS OF TREATING CANCER WITH A COMBINATION OF AN ANTI-PD-1 ANTIBODY AND AN ANTI-TISSUE FACTOR ANTIBODY-DRUG CONJUGATE | GENMAB A/S (DK) | 2019-11-14 | — | — | WO | disclosed |