Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.48 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | NPY4R | P50391 | 9/20 | 0.48 |
| ▸ | NPY1R | P25929 | 7/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.48 |
| ▸ | NPY2R | P49146 | 4/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.48 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.46 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21570993 | 1.00 | OPRM1 (0.48) | OPRM1NPFFR1NPFFR2OPRD1NPY4R | |
| SCHEMBL21570990 | 1.00 | OPRM1 (0.48) | OPRM1NPFFR1NPFFR2OPRD1NPY4R | |
| SCHEMBL21570976 | 0.96 | NTMT1 (0.51) | OPRM1NPFFR1NPFFR2OPRD1NPY4R | |
| SCHEMBL21571015 | 0.96 | NTMT1 (0.51) | OPRM1NPFFR1NPFFR2OPRD1NPY4R | |
| SCHEMBL21579316 | 0.96 | NTMT1 (0.51) | OPRM1NPFFR1NPFFR2OPRD1NPY4R | |
| SCHEMBL21570973 | 0.96 | NTMT1 (0.51) | OPRM1NPFFR1NPFFR2OPRD1NPY4R | |
| SCHEMBL21570970 | 0.96 | NTMT1 (0.51) | OPRM1NPFFR1NPFFR2OPRD1NPY4R | |
| SCHEMBL21579283 | 0.92 | NTMT1 (0.47) | OPRM1NPFFR1NPFFR2OPRD1NPY4R | |
| SCHEMBL21570975 | 0.90 | NTMT1 (0.51) | OPRM1ITGB1ITGA4NTMT1 | |
| SCHEMBL21570977 | 0.90 | NTMT1 (0.51) | OPRM1ITGB1ITGA4NTMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260085093-A1 | INHIBITORS FOR PROTEIN N-TERMINAL METHYLTRANSFERASE AND USES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2026-03-26 | — | — | US | disclosed |
| US-20260078147-A1 | INHIBITORS FOR PROTEIN N-TERMINAL METHYLTRANSFERASE AND USES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2026-03-19 | — | — | US | disclosed |
| US-12479887-B2 | Inhibitors for protein n-terminal methyltransferase and uses thereof | PURDUE RESEARCH FOUNDATION (US) | 2025-11-25 | — | — | US | disclosed |
| US-20190352338-A1 | INHIBITORS FOR PROTEIN N-TERMINAL METHYLTRANSFERASE AND USES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2019-11-21 | — | — | US | disclosed |
| US-20190352338-A1 | INHIBITORS FOR PROTEIN N-TERMINAL METHYLTRANSFERASE AND USES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2019-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260085093-A1 | INHIBITORS FOR PROTEIN N-TERMINAL METHYLTRANSFERASE AND USES THEREOF | GNMT, PRMT5, INMT | OPRM1 598/4885NPFFR1 2810/4885NPFFR2 2370/4885 |
| US-12479887-B2 | Inhibitors for protein n-terminal methyltransferase and uses thereof | GNMT, PRMT1, PRMT5 | OPRM1 1865/4885NPFFR1 4072/4885NPFFR2 4133/4885 |
| US-20260078147-A1 | INHIBITORS FOR PROTEIN N-TERMINAL METHYLTRANSFERASE AND USES THEREOF | SMYD2, INMT, PRMT6 | OPRM1 1262/4885NPFFR1 3423/4885NPFFR2 2991/4885 |
| US-20190352338-A1 | INHIBITORS FOR PROTEIN N-TERMINAL METHYLTRANSFERASE AND USES THEREOF | GNMT, PRMT1, PRMT5 | OPRM1 1865/4885NPFFR1 4072/4885NPFFR2 4133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.