SCHEMBL21572115

SCHEMBL21572115

CC(C)(C)OC1C(CO)OC(C(C)(C)N)C(O)C1O

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20746624 0.86 L3MBTL1 (0.38) L3MBTL1MAPT
SCHEMBL10820248 0.82 L3MBTL1 (0.40) L3MBTL1MAPT
SCHEMBL24004413 0.79 L3MBTL1 (0.53) L3MBTL1MAPT
SCHEMBL24004411 0.79 L3MBTL1 (0.53) L3MBTL1MAPT
SCHEMBL13034058 0.79 L3MBTL1 (0.53) L3MBTL1MAPT
SCHEMBL17811737 0.79 AMY1A (0.41) L3MBTL1MAPT
SCHEMBL21565006 0.78 L3MBTL1 (0.46) L3MBTL1MAPT
SCHEMBL27055134 0.77 L3MBTL1 (0.39) L3MBTL1MAPT
SCHEMBL19790925 0.77 L3MBTL1 (0.36) L3MBTL1MAPT
SCHEMBL19860207 0.77 L3MBTL1 (0.36) L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11026965-B2 Nitric oxide-releasing cyclodextrins as biodegradable antibacterial scaffolds and methods pertaining thereto THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2021-06-08 — — US disclosed
US-20190343869-A1 NITRIC OXIDE-RELEASING CYCLODEXTRINS AS BIODEGRADABLE ANTIBACTERIAL SCAFFOLDS AND METHODS PERTAINING THERETO THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2019-11-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190343869-A1 NITRIC OXIDE-RELEASING CYCLODEXTRINS AS BIODEGRADABLE ANTIBACTERIAL SCAFFOLDS AND METHODS PERTAINING THERETO NOS1, NOS2, NOS3 L3MBTL1 3969/4885MAPT 2791/4885
US-11026965-B2 Nitric oxide-releasing cyclodextrins as biodegradable antibacterial scaffolds and methods pertaining thereto NOS1, NOS2, NOS3 L3MBTL1 3969/4885MAPT 2791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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