Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.46 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.46 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.40 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | PNP | P00491 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL864311 | 0.77 | ALDH1A1 (0.42) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL17372398 | 0.77 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL19529689 | 0.77 | LMNA (0.46) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL17176923 | 0.69 | PNP (0.50) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL215723 | 0.69 | PNP (0.30) | PNP | |
| Adenine SCHEMBL29355156 | 0.63 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| Adenine SCHEMBL1331751 | 0.63 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| Adenine SCHEMBL29466915 | 0.63 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| Adenine SCHEMBL8111 | 0.63 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| Adenine SCHEMBL3414606 | 0.63 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 295 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8618074-B2 | GPCR enhanced neuroprotection to treat brain injury | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-12-31 | — | — | US | claimed |
| US-20100216735-A1 | GPCR ENHANCED NEUROPROTECTION TO TREAT BRAIN INJURY | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2010-08-26 | — | — | US | claimed |
| WO-2008113072-A2 | GPCR ENHANCED NEUROPROTECTION TO TREAT BRAIN INJURY | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2008-09-18 | — | — | WO | claimed |
| EP-1959968-A2 | MODULATION OF THE P2Y2 RECEPTOR PATHWAY | P2-Science APS (DK) | 2008-08-27 | — | — | EP | claimed |
| EP-1545407-A4 | VAGINAL HEALTH PRODUCTS | KIMBERLY CLARK CO (US) | 2008-05-07 | — | — | EP | claimed |
| WO-2007065437-A2 | MODULATION OF THE P2Y2 RECEPTOR PATHWAY | P2-SCIENCE APS (DK) | 2007-06-14 | — | — | WO | claimed |
| US-6977246-B2 | Certain dinucleotides and their use as modulators of mucociliary clearance and ciliary beat frequency | INSPIRE PHARMACEUTICALS, INC. (US) | 2005-12-20 | — | — | US | claimed |
| CN-1678261-A | Vaginal health product | KIMBERLY CLARK CO (US) | 2005-10-05 | — | — | CN | claimed |
| EP-1545407-A2 | VAGINAL HEALTH PRODUCTS | Kimberly-Clark Worldwide, Inc. (US) | 2005-06-29 | — | — | EP | claimed |
| US-20040063787-A1 | Vaginal health products | KIMBERLY-CLARK WORLDWIDE, INC. | 2004-04-01 | — | — | US | claimed |
| US-5763447-A | Method of preventing or treating pneumonia in immobilized patients with uridine triphosphates and related compounds | INSPIRE PHARMACEUTICALS (US) | 1998-06-09 | — | — | US | claimed |
| WO-1998019685-A1 | METHOD OF TREATING BRONCHITIS WITH URIDINE TRIPHOSPHATES AND RELATED COMPOUNDS | INSPIRE PHARMACEUTICALS, INC. (US) | 1998-05-14 | — | — | WO | claimed |
| WO-1998015835-A1 | METHOD OF EARLY LUNG CANCER DETECTION VIA SPUTUM INDUCTION AND ANALYSIS OF SPUTUM TO DETECT CANCER ASSOCIATED SUBSTANCES | INSPIRE PHARMACEUTICALS, INC. (US) | 1998-04-16 | — | — | WO | claimed |
| WO-1997035591-A9 | METHOD OF TREATING CILIARY DYSKINESIA WITH URIDINE TRIPHOSPHATES AND RELATED COMPOUNDS | — | 1998-02-19 | — | — | WO | claimed |
| WO-1998003177-A1 | METHOD OF TREATING SINUSITIS WITH URIDINE TRIPHOSPHATES AND RELATED COMPOUNDS | INSPIRE PHARMACEUTICALS, INC. (US) | 1998-01-29 | — | — | WO | claimed |
| WO-1998003182-A2 | USE OF URIDINE TRIPHOSPHATES AND RELATED COMPOUNDS FOR THE PREVENTION AND TREATMENT OF PNEUMONIA IN IMMOBILIZED PATIENTS | INSPIRE PHARMACEUTICALS, INC. (US) | 1998-01-29 | — | — | WO | claimed |
| WO-1997035591-A2 | METHOD OF TREATING CILIARY DYSKINESIA WITH URIDINE TRIPHOSPHATES AND RELATED COMPOUNDS | INSPIRE PHARMACEUTICALS, INC. (US) | 1997-10-02 | — | — | WO | claimed |
| WO-1997029756-A1 | METHOD OF TREATING OTITIS MEDIA WITH URIDINE TRIPHOSPHATES AND RELATED COMPOUNDS | INSPIRE PHARMACEUTICALS, INC. (US) | 1997-08-21 | — | — | WO | claimed |
| EP-0540686-B1 | 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES | US COMMERCE (US) | 1995-08-30 | — | — | EP | claimed |
| WO-1992001700-A1 | 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) | 1992-02-06 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216735-A1 | GPCR ENHANCED NEUROPROTECTION TO TREAT BRAIN INJURY | P2RY1, P2RY2, P2RY11 | PI4KA 1241/4885PI4K2B 1555/4885PI4K2A 1282/4885 |
| US-20040063787-A1 | Vaginal health products | MUC1, PGF, AQP3 | PI4KA 3616/4885PI4K2B 3534/4885PI4K2A 3448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.