Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20434827 | 0.89 | EPHX2 (0.31) | EPHX2 | |
| SCHEMBL10202606 | 0.80 | DPP4 (0.35) | EPHX2RIPK1MEN1KMT2A | |
| SCHEMBL15490630 | 0.78 | RORC (0.33) | EPHX2RIPK1MEN1KMT2A | |
| SCHEMBL18702002 | 0.78 | EPHX2 (0.35) | EPHX2RIPK1MEN1KMT2A | |
| SCHEMBL24621674 | 0.77 | MEN1 (0.32) | EPHX2RIPK1MEN1KMT2A | |
| SCHEMBL21577564 | 0.77 | RIPK1 (0.32) | EPHX2RIPK1MEN1KMT2A | |
| SCHEMBL18701918 | 0.77 | MEN1 (0.32) | RIPK1MEN1KMT2A | |
| SCHEMBL12208870 | 0.75 | EPHX2 (0.33) | EPHX2RIPK1MEN1KMT2A | |
| SCHEMBL17886961 | 0.73 | MEN1 (0.34) | EPHX2RIPK1MEN1KMT2A | |
| SCHEMBL21137552 | 0.72 | HSD11B1 (0.41) | EPHX2RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11066419-B2 | 1H-pyrrole-2,5-dione compounds and methods of using same | Frequency Therapeutics, Inc. (US) | 2021-07-20 | — | — | US | disclosed |
| US-20200113913-A1 | METHODS FOR HAIR FOLLICLE STEM CELL PROLIFERATION | Frequency Therapeutics, Inc. | 2020-04-16 | — | — | US | disclosed |
| US-20190352313-A1 | 1H-PYRROLE-2,5-DIONE COMPOUNDS AND METHODS OF USING THEM TO INDUCE SELF-RENEWAL OF STEM/PROGENITOR SUPPORTING CELLS | Frequency Therapeutics, Inc. | 2019-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200113913-A1 | METHODS FOR HAIR FOLLICLE STEM CELL PROLIFERATION | SHH, WNT3A, WNT1 | EPHX2 1940/4885RIPK1 1824/4885MEN1 4799/4885 |
| US-11066419-B2 | 1H-pyrrole-2,5-dione compounds and methods of using same | MKI67, PROX1, DCX | EPHX2 1675/4885RIPK1 2505/4885MEN1 3191/4885 |
| US-20190352313-A1 | 1H-PYRROLE-2,5-DIONE COMPOUNDS AND METHODS OF USING THEM TO INDUCE SELF-RENEWAL OF STEM/PROGENITOR SUPPORTING CELLS | MCL1, PROX1, MKI67 | EPHX2 2483/4885RIPK1 2083/4885MEN1 3908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.