Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 5/20 | 0.53 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.53 |
| ▸ | HTR3B | O95264 | 3/20 | 0.53 |
| ▸ | HTR3A | P46098 | 3/20 | 0.53 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.53 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 9/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 9/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.50 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL182813 | 0.92 | ADRB1 (0.61) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| Bromide SCHEMBL11430793 | 0.90 | ADRB1 (0.59) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL114702 | 0.81 | CHKA (0.46) | NCF1KDM4EALDH1A1LMNA | |
| SCHEMBL41297 | 0.81 | CHKA (0.52) | KDM4EALDH1A1LMNA | |
| SCHEMBL4613193 | 0.81 | ADRB1 (0.55) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL3066756 | 0.80 | ADRB1 (0.83) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL4719117 | 0.80 | ADRB1 (0.47) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL1900341 | 0.79 | ALDH1A1 (0.52) | KDM4EALDH1A1LMNA | |
| SCHEMBL146936 | 0.79 | ALDH1A1 (0.52) | KDM4EALDH1A1LMNA | |
| SCHEMBL17276864 | 0.79 | ADRB1 (0.68) | ADRB1HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160222014-A1 | COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS | ASANA BIOSCIENCES, LLC (US) | 2016-08-04 | — | — | US | claimed |
| WO-2015038417-A1 | COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS | ASANA BIOSCIENCES, LLC (US) | 2015-03-19 | — | — | WO | claimed |
| US-7700630-B2 | Heterocyclic compounds, methods for the preparation thereof, and uses thereof | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-04-20 | — | — | US | claimed |
| US-7244745-B2 | Heterocyclic compounds, methods for the preparation thereof, and uses thereof | MEMORY PHARMACEUTICALS CORP. (US) | 2007-07-17 | — | — | US | claimed |
| WO-2024145505-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | ACRIVON THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |
| EP-3323816-A1 | NOVEL PYRAZOLE DERIVATIVE | Green Tech Co., Ltd. (JP) | 2018-05-23 | — | — | EP | disclosed |
| US-20160222014-A1 | COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS | ASANA BIOSCIENCES, LLC (US) | 2016-08-04 | — | — | US | disclosed |
| US-9399635-B2 | Pyrazole derivative | GREEN TECH CO., LTD. (JP) | 2016-07-26 | — | — | US | disclosed |
| WO-2015038417-A1 | COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS | ASANA BIOSCIENCES, LLC (US) | 2015-03-19 | — | — | WO | disclosed |
| US-20140088029-A1 | NOVEL PYRAZOLE DERIVATIVE | PHARMA EIGHT CO., LTD. (JP) | 2014-03-27 | — | — | US | disclosed |
| EP-2698368-A1 | NOVEL PYRAZOLE DERIVATIVE | Pharma Eight Co. Ltd (JP) | 2014-02-19 | — | — | EP | disclosed |
| US-8288396-B2 | Pyrimidopyrimidoindazole derivative | MSDKK (JP) | 2012-10-16 | — | — | US | disclosed |
| WO-2010098367-A1 | PYRIMIDOPYRIMIDOINDAZOLE DERIVATIVE | BANYU PHARMACEUTICAL CO.,LTD. (JP) | 2010-09-02 | — | — | WO | disclosed |
| US-20100173891-A1 | HETEROCYCLIC COMPOUNDS, METHODS FOR THE PREPARATION THEREOF, AND USES THEREOF | HERBERT BRIAN | 2010-07-08 | — | — | US | disclosed |
| US-7700630-B2 | Heterocyclic compounds, methods for the preparation thereof, and uses thereof | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-04-20 | — | — | US | disclosed |
| US-20090105215-A1 | 3-Quinolin-2-ylmethylene-3,4,5,6-terahydro[2,3']bipyridinyl; for therapy and prophylaxis of psychotic diseases, neurodegenerative diseases involving a dysfunction of the cholinergic system | HERBERT BRIAN | 2009-04-23 | — | — | US | disclosed |
| US-7244745-B2 | Heterocyclic compounds, methods for the preparation thereof, and uses thereof | MEMORY PHARMACEUTICALS CORP. (US) | 2007-07-17 | — | — | US | disclosed |
| EP-1531820-A1 | ANABASEINE DERIVATIVES USEFUL IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | Memory Pharmaceuticals Corporation (US) | 2005-05-25 | — | — | EP | disclosed |
| US-20040229868-A1 | Heterocyclic compounds, methods for the preparation thereof, and uses thereof | MEMORY PHARMACEUTICALS CORP. | 2004-11-18 | — | — | US | disclosed |
| WO-2004019943-A1 | ANABASEINE DERIVATIVES USEFUL IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | MEMORY PHARMACEUTICALS CORPORATION (US) | 2004-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229868-A1 | Heterocyclic compounds, methods for the preparation thereof, and uses thereof | CHRNA1, CHRNA4, CHRNA3 | ADRB1 44/4885HTR3E 279/4885HTR3B 128/4885 |
| US-20090105215-A1 | 3-Quinolin-2-ylmethylene-3,4,5,6-terahydro[2,3']bipyridinyl; for therapy and prophylaxis of psychotic diseases, neurodegenerative diseases involving a dysfunction of the cholinergic system | CHRNA3, CHRNA2, CHRNA5 | ADRB1 76/4885HTR3E 180/4885HTR3B 89/4885 |
| US-20140088029-A1 | NOVEL PYRAZOLE DERIVATIVE | PSEN2, MAPT, PSEN1 | ADRB1 46/4885HTR3E 993/4885HTR3B 239/4885 |
| US-20160222014-A1 | COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS | SRC, PTK2, FYN | ADRB1 2885/4885HTR3E 1821/4885HTR3B 1989/4885 |
| US-20100173891-A1 | HETEROCYCLIC COMPOUNDS, METHODS FOR THE PREPARATION THEREOF, AND USES THEREOF | CHRM3, CHRNA1, CHRNA5 | ADRB1 84/4885HTR3E 366/4885HTR3B 173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.