Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ocarocoxib SCHEMBL5796379 | 1.00 | PTGS2 (1.00) | PTGS2PTGS1 | |
| Ocarocoxib SCHEMBL5708929 | 1.00 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL6094274 | 0.85 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL6092337 | 0.85 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL16893629 | 0.84 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL16893541 | 0.84 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL5798438 | 0.84 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL16893539 | 0.84 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL16893626 | 0.84 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL6092246 | 0.83 | PTGS2 (0.75) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 336 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3664800-B1 | THERAPEUTIC FORMULATIONS COMPRISING COX-2 INHIBITOR AND USES THEREOF | DECHRA VETERINARY PRODUCTS LLC (US) | 2024-05-08 | — | — | EP | claimed |
| EP-3664800-A1 | THERAPEUTIC FORMULATIONS AND USES THEREOF | Piedmont Animal Health Inc. (US) | 2020-06-17 | — | — | EP | claimed |
| US-20190142789-A1 | THERAPEUTIC FORMULATIONS AND USES THEREOF | PIEDMONT ANIMAL HEALTH LLC | 2019-05-16 | — | — | US | claimed |
| WO-2019032910-A1 | THERAPEUTIC FORMULATIONS AND USES THEREOF | PIEDMONT ANIMAL HEALTH LLC (US) | 2019-02-14 | — | — | WO | claimed |
| US-9447065-B2 | Pharmaceutical composition | RAQUALIA PHARMA INC. (JP) | 2016-09-20 | — | — | US | claimed |
| EP-2979695-A1 | THERAPEUTIC AGENT FOR EYE DISORDER | AskAt Inc. (JP) | 2016-02-03 | — | — | EP | claimed |
| US-20160008317-A1 | THERAPEUTIC AGENT FOR OCULAR DISEASE | ASKAT INC. (JP) | 2016-01-14 | — | — | US | claimed |
| US-20140256804-A1 | PHARMACEUTICAL COMPOSITION | RAQUALIA PHARMA INC. (JP) | 2014-09-11 | — | — | US | claimed |
| EP-2769718-A1 | MEDICINAL COMPOSITION | RaQualia Pharma Inc. (JP) | 2014-08-27 | — | — | EP | claimed |
| EP-1725222-A2 | METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING PSYCHIATRIC DISORDERS WITH COX-2 INHIBITORS ALONE AND IN COMBINATION WITH ANTIDEPRESSANT AGENTS | Pharmacia Corporation (US) | 2006-11-29 | — | — | EP | claimed |
| WO-2003015799-A1 | COMPOSITIONS FOR THE TREATMENT AND PREVENTION OF PAIN AND INFLAMMATION WITH A CYCLOOXYGENASE-2 SELECTIVE INHIBITOR AND CHONDROITIN SULFATE | PHARMACIA CORPORATION (US) | 2003-02-27 | — | — | WO | claimed |
| WO-2002096516-A1 | USE OF COMPOSITIONS COMPRISING CYCLOOXYGENASE-2 SELECTIVE INHIBITORS IN COMBINATION WITH RADIATION FOR INHIBITION OR PREVENTION OF CARDIOVASCULAR DISEASE | PHARMACIA CORPORATION (US) | 2002-12-05 | — | — | WO | claimed |
| WO-2002085459-A2 | ANTIANGIOGENIC COMBINATION THERAPY FOR THE TREATMENT OF CANCER | PHARMACIA CORPORATION (US) | 2002-10-31 | — | — | WO | claimed |
| WO-2002078626-A2 | THERAPEUTIC COMBINATIONS FOR CARDIOVASCULAR AND INFLAMMATORY INDICATIONS | PHARMACIA CORPORATION (US) | 2002-10-10 | — | — | WO | claimed |
| US-20020103141-A1 | Antiangiogenic combination therapy for the treatment of cancer | PHARMACIA CORPORATION | 2002-08-01 | — | — | US | claimed |
| US-20020077328-A1 | Selective cyclooxygenase-2 inhibitors and vasomodulator compounds for generalized pain and headache pain | PHARMACIA CORPORATION | 2002-06-20 | — | — | US | claimed |
| CN-1257489-A | Substituted benzopyran derivatives for the treatment of inflammation | SEARLE & CO (US) | 2000-06-21 | — | — | CN | claimed |
| US-6034256-A | CYCLOOXYGEASE INHIBITOR | G.D. SEARLE & CO. (US) | 2000-03-07 | — | — | US | claimed |
| EP-0977748-A1 | SUBSTITUTED BENZOPYRAN DERIVATIVES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 2000-02-09 | — | — | EP | claimed |
| WO-1998047890-A1 | SUBSTITUTED BENZOPYRAN DERIVATIVES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-10-29 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256804-A1 | PHARMACEUTICAL COMPOSITION | CYP2C19, CYP2C9, CYP3A5 | PTGS2 36/4885PTGS1 40/4885 |
| US-20020077328-A1 | Selective cyclooxygenase-2 inhibitors and vasomodulator compounds for generalized pain and headache pain | PTGIR, VASP, TRPV2 | PTGS2 4/4885PTGS1 8/4885 |
| US-20020103141-A1 | Antiangiogenic combination therapy for the treatment of cancer | TOP2A, TOP2B, TOP1 | PTGS2 4/4885PTGS1 6/4885 |
| US-20160008317-A1 | THERAPEUTIC AGENT FOR OCULAR DISEASE | ALDH1A2, PDE6C, PDE6A | PTGS2 692/4885PTGS1 272/4885 |
| US-20190142789-A1 | THERAPEUTIC FORMULATIONS AND USES THEREOF | PTGES2, PTGES, PTGS2 | PTGS2 3/4885PTGS1 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.