SCHEMBL2158393

SCHEMBL2158393

Cc1c(S(C)(=O)=O)cc[n+]([O-])c1C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
ENPP2 Q13822 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL667046 0.69 CCR5 (0.33)
SCHEMBL712432 0.67 ALDH1A1 (0.34)
SCHEMBL8914541 0.66
SCHEMBL27957597 0.66
SCHEMBL29964915 0.66
SCHEMBL8802293 0.66 CYP3A4 (0.40)
Hydrochloric Acid SCHEMBL28082955 0.66 ALDH1A1 (0.34)
SCHEMBL11956551 0.64 IDO1 (0.33) ENPP2
SCHEMBL18230170 0.64 SMN1; SMN2 (0.32) SMN1; SMN2ENPP2
SCHEMBL18000415 0.64 TSHR (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8513427-B2 Compounds for producing substituted sulfoxides, process for producing the same and use thereof MATRIX LABORATORIES LIMITED (IN) 2013-08-20 US claimed
EP-2342193-B1 NOVEL COMPOUNDS FOR PRODUCING SUBSTITUTED SULFOXIDES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF MATRIX LAB LTD (IN) 2013-06-05 EP claimed
US-20110184182-A1 COMPOUNDS FOR PRODUCING SUBSTITUTED SULFOXIDES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF MATRIX LABORATORIES LIMITED (IN) 2011-07-28 US claimed
EP-2342193-A2 NOVEL COMPOUNDS FOR PRODUCING SUBSTITUTED SULFOXIDES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF Matrix Laboratories Limited (IN) 2011-07-13 EP claimed
WO-2010035283-A2 NOVEL COMPOUNDS FOR PRODUCING SUBSTITUTED SULFOXIDES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF MATRIX LABORATORIES LIMITED (IN) 2010-04-01 WO claimed
US-20130231486-A1 COMPOUNDS FOR PRODUCING SUBSTITUTED SULFOXIDES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF MATRIX LABORATORIES LIMITED (IN) 2013-09-05 US disclosed
US-20130231486-A1 COMPOUNDS FOR PRODUCING SUBSTITUTED SULFOXIDES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF MATRIX LABORATORIES LIMITED (IN) 2013-09-05 US disclosed
US-8513427-B2 Compounds for producing substituted sulfoxides, process for producing the same and use thereof MATRIX LABORATORIES LIMITED (IN) 2013-08-20 US disclosed
US-8513427-B2 Compounds for producing substituted sulfoxides, process for producing the same and use thereof MATRIX LABORATORIES LIMITED (IN) 2013-08-20 US disclosed
EP-2342193-B1 NOVEL COMPOUNDS FOR PRODUCING SUBSTITUTED SULFOXIDES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF MATRIX LAB LTD (IN) 2013-06-05 EP disclosed
US-20110184182-A1 COMPOUNDS FOR PRODUCING SUBSTITUTED SULFOXIDES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF MATRIX LABORATORIES LIMITED (IN) 2011-07-28 US disclosed
US-20110184182-A1 COMPOUNDS FOR PRODUCING SUBSTITUTED SULFOXIDES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF MATRIX LABORATORIES LIMITED (IN) 2011-07-28 US disclosed
EP-2342193-A2 NOVEL COMPOUNDS FOR PRODUCING SUBSTITUTED SULFOXIDES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF Matrix Laboratories Limited (IN) 2011-07-13 EP disclosed
WO-2010035283-A2 NOVEL COMPOUNDS FOR PRODUCING SUBSTITUTED SULFOXIDES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF MATRIX LABORATORIES LIMITED (IN) 2010-04-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130231486-A1 COMPOUNDS FOR PRODUCING SUBSTITUTED SULFOXIDES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF SQOR, SMOX, CBS L3MBTL1 4229/4885SMN1; SMN2 1394/4885ENPP2 1070/4885
US-20110184182-A1 COMPOUNDS FOR PRODUCING SUBSTITUTED SULFOXIDES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF SQOR, SMOX, CBS L3MBTL1 4229/4885SMN1; SMN2 1394/4885ENPP2 1070/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.