Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 4/20 | 0.54 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.54 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | OXTR | P30559 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | TPMT | P51580 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17321082 | 0.82 | L3MBTL1 (0.64) | MCHR1L3MBTL1CA12CA1CA2 | |
| SCHEMBL2158629 | 0.81 | HSD17B1 (0.47) | HSD17B2HSD17B1MCHR1L3MBTL1ALDH1A1 | |
| SCHEMBL2158030 | 0.80 | CNR1 (0.52) | HSD17B2HSD17B1L3MBTL1OXTRALDH1A1 | |
| SCHEMBL2157643 | 0.79 | HSD17B2 (0.46) | HSD17B2HSD17B1OXTRALDH1A1CYP3A4 | |
| SCHEMBL2157847 | 0.78 | HSD17B1 (0.50) | HSD17B2HSD17B1OXTRHTTNPSR1 | |
| SCHEMBL2157714 | 0.78 | ACLY (0.52) | HSD17B2HSD17B1L3MBTL1OXTRALDH1A1 | |
| SCHEMBL17107127 | 0.77 | GRM1 (0.62) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL2157779 | 0.77 | TUBB4A (0.47) | HSD17B2HSD17B1MCHR1CA12CA1 | |
| SCHEMBL3811638 | 0.76 | MAPT (0.45) | HSD17B2HSD17B1MCHR1L3MBTL1CA12 | |
| SCHEMBL2158482 | 0.74 | TRPV1 (0.50) | HSD17B2HSD17B1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985769-B2 | Compounds and methods for the treatment or prevention of Flavivirus infections | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-07-26 | — | — | US | disclosed |
| US-20060142347-A1 | Compounds and methods for the treatment or prevention of Flavivirus infections | VERTEX PHARMACEUTICALS (CANADA) INCORPORATED (CA) | 2006-06-29 | — | — | US | disclosed |
| US-6881741-B2 | Compounds and methods for the treatment or prevention of Flavivirus infections | VIROCHEM PHARMA INC. (CA) | 2005-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142347-A1 | Compounds and methods for the treatment or prevention of Flavivirus infections | HAVCR2, ZC3HAV1, MAVS | HSD17B2 1131/4885HSD17B1 740/4885MCHR1 3432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.