SCHEMBL2158677

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17541741	0.78	IDO1 (0.47)	ENPP2IDO1KDM4ENPBWR1NPC1
	SCHEMBL1440897	0.78	IDO1 (0.53)	ENPP2IDO1NPBWR1ALDH1A1NPC1
	SCHEMBL970723	0.78	IDO1 (0.61)	ENPP2IDO1KDM4ECYP3A4NPBWR1
	SCHEMBL9234967	0.78	NISCH (0.48)	ENPP2IDO1KDM4ENPBWR1ALDH1A1
	SCHEMBL4233813	0.78	IDO1 (0.56)	ENPP2IDO1NPBWR1ALDH1A1GAA
	SCHEMBL23718811	0.78	IDO1 (0.50)	ENPP2IDO1NPBWR1ALDH1A1NPC1
	SCHEMBL10022370	0.78	IDO1 (0.47)	ENPP2IDO1KDM4ECYP3A4NPBWR1
	SCHEMBL5372567	0.78	ENPP2 (0.51)	ENPP2IDO1
	SCHEMBL2721372	0.77	IDO1 (0.60)	ENPP2IDO1KDM4ENPBWR1ALDH1A1
	SCHEMBL3080603	0.76	ENPP2 (1.00)	ENPP2IDO1KDM4EALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.