SCHEMBL21586948

SCHEMBL21586948

CC(C)(C)c1cc(OCCCO)cc(-n2nc3ccc(Sc4ccccc4)cc3n2)c1O

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ACSS2 Q9NR19 1/20 0.34
MAPK14 Q16539 2/20 0.32
VCAM1 P19320 2/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
ESRRA P11474 1/20 0.31
EGLN2 Q96KS0 1/20 0.31
EGLN1 Q9GZT9 1/20 0.31
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
PKM P14618 1/20 0.30
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30
MCL1 Q07820 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
FGFR1 P11362 1/20 0.30
SRC P12931 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31651454 0.93 MAPK14 (0.34) MAPK14VCAM1NPC1RAB9AKDM4E
SCHEMBL21586961 0.88 FDPS (0.36) MAPK14
SCHEMBL23636572 0.87 VCAM1 (0.33) VCAM1
SCHEMBL21586965 0.87 NPC1 (0.40) ACSS2VCAM1NPC1RAB9AKDM4E
SCHEMBL23636568 0.86 PTGS2 (0.33) VCAM1
SCHEMBL8040102 0.85 NPC1 (0.32) NPC1RAB9AEGLN2EGLN1LMNA
SCHEMBL23638712 0.83 NPC1 (0.37) ACSS2VCAM1NPC1RAB9AKDM4E
SCHEMBL23636580 0.83 VCAM1 (0.33) VCAM1
SCHEMBL21586947 0.82 PDE2A (0.36) ACSS2VCAM1NPC1RAB9AKDM4E
SCHEMBL8441278 0.82 CA1 (0.39) ACSS2NPC1RAB9ALMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250216700-A1 REACTIVE UV ABSORBERS AND ANTI-BLUE LIGHT EYE DEVICE COMPRISING THE SAME EVERLIGHT CHEMICAL INDUSTRIAL CORPORATION (TW) 2025-07-03 US disclosed
EP-3578550-B1 NOVEL RED-SHIFTING BENZOTRIAZOLE UV ABSORBERS EVERLIGHT CHEM IND CORP (TW) 2023-08-16 EP disclosed
EP-3578550-A1 NOVEL BENZOTRIAZOLE UV ABSORBER WITH RED SHIFT AND USE THEREOF Everlight Chemical Industrial Corporation (TW) 2019-12-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250216700-A1 REACTIVE UV ABSORBERS AND ANTI-BLUE LIGHT EYE DEVICE COMPRISING THE SAME UACA, IK, CRY2 ACSS2 2654/4885MAPK14 3276/4885VCAM1 2486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.