Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2545801 | 0.84 | ALDH1A1 (0.39) | ELANEGLASMN1; SMN2FAAHPOLB | |
| SCHEMBL31400333 | 0.80 | ELANE (0.47) | ELANESMN1; SMN2POLBALDH1A1TSHR | |
| SCHEMBL13024386 | 0.78 | FAAH (0.39) | ELANEFAAHALDH1A1TSHRL3MBTL1 | |
| SCHEMBL20269905 | 0.75 | LMNA (0.50) | ELANESMN1; SMN2FAAHPOLBALDH1A1 | |
| SCHEMBL344479 | 0.75 | ALDH1A1 (0.39) | ELANEGLASMN1; SMN2FAAHPOLB | |
| SCHEMBL24276762 | 0.74 | ADORA3 (0.40) | SMN1; SMN2POLBALDH1A1NPSR1 | |
| SCHEMBL3436434 | 0.74 | L3MBTL1 (0.43) | GLASMN1; SMN2ALDH1A1L3MBTL1ADORA1 | |
| SCHEMBL6417297 | 0.74 | CYP1A2 (0.40) | FAAHPOLBALDH1A1HPGDGAA | |
| SCHEMBL24049629 | 0.74 | MAPT (0.39) | ELANEGLASMN1; SMN2FAAHPOLB | |
| SCHEMBL23500483 | 0.74 | FAAH (0.38) | ELANEFAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3805217-A1 | ERK INHIBITOR AND USE THEREOF | Betta Pharmaceuticals Co., Ltd (CN) | 2021-04-14 | — | — | EP | disclosed |
| WO-2019233456-A1 | ERK INHIBITOR AND USE THEREOF | 贝达药业股份有限公司 (CN) | 2019-12-12 | — | — | WO | disclosed |
| WO-2019233457-A1 | ERK INHIBITOR AND USE THEREOF | 贝达药业股份有限公司 (CN) | 2019-12-12 | — | — | WO | disclosed |