Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21591469 | 0.85 | ACHE (0.41) | ACHEPTGS1PTGS2CYP1A2GAA | |
| SCHEMBL31217580 | 0.77 | MAOB (0.62) | ACHECYP1A2GAAALOX15KDM4E | |
| SCHEMBL266461 | 0.77 | GABRP (0.60) | ACHECYP1A2GAAALOX15KDM4E | |
| SCHEMBL9432919 | 0.76 | AHR (0.52) | ACHEPTGS1PTGS2CYP1A2GAA | |
| SCHEMBL15663163 | 0.76 | ALOX15 (0.61) | ACHEPTGS1PTGS2CYP1A2GAA | |
| SCHEMBL31217562 | 0.73 | ACHE (0.58) | ACHEPTGS2CYP1A2GAAALOX15 | |
| SCHEMBL25818860 | 0.73 | KDM4E (0.50) | ACHEPTGS1PTGS2CYP1A2GAA | |
| 2,7-Dimethylchromone SCHEMBL7600130 | 0.72 | ALDH1A1 (0.64) | ACHECYP1A2GAAALOX15KDM4E | |
| SCHEMBL266614 | 0.72 | MAPT (0.63) | ACHEKDM4ETP53MAPTHSD17B10 | |
| SCHEMBL6331783 | 0.72 | AKR1B1 (0.58) | PTGS1KDM4EMAPTHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3807264-A1 | MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | Ryvu Therapeutics S.A. (PL) | 2021-04-21 | — | — | EP | disclosed |
| WO-2019238786-A1 | MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | Ryvu Therapeutics S.A. (PL) | 2019-12-19 | — | — | WO | disclosed |