Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SIK1 | P57059 | 12/20 | 0.38 |
| ▸ | SIK2 | Q9H0K1 | 12/20 | 0.38 |
| ▸ | SIK3 | Q9Y2K2 | 12/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.38 |
| ▸ | GAK | O14976 | 1/20 | 0.38 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | YES1 | P07947 | 1/20 | 0.38 |
| ▸ | LYN | P07948 | 1/20 | 0.38 |
| ▸ | HCK | P08631 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | ACVR2A | P27037 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30130915 | 1.00 | TAS1R3 (0.43) | TAS1R3TAS1R1TAS1R2POLBSIK1 | |
| SCHEMBL21593402 | 0.88 | SIK1 (0.48) | POLBSIK1SIK2SIK3ALDH1A1 | |
| SCHEMBL21593393 | 0.77 | PTGS2 (0.34) | SIK1SIK2SIK3ALDH1A1MEN1 | |
| SCHEMBL21591061 | 0.77 | KCNH2 (0.49) | TAS1R3TAS1R1TAS1R2POLBKCNH2 | |
| SCHEMBL23162335 | 0.77 | SIK1 (0.42) | SIK1SIK2SIK3ALDH1A1BMPR1B | |
| SCHEMBL30130962 | 0.75 | ALDH1A1 (0.39) | TAS1R3TAS1R1TAS1R2POLBSIK1 | |
| SCHEMBL21593394 | 0.75 | ALDH1A1 (0.39) | TAS1R3TAS1R1TAS1R2POLBSIK1 | |
| SCHEMBL21593290 | 0.75 | SIK1 (0.42) | POLBSIK1SIK2SIK3ALDH1A1 | |
| SCHEMBL29954128 | 0.74 | SIK1 (0.37) | SIK1SIK2SIK3BMPR1BGAK | |
| SCHEMBL22726559 | 0.72 | SIK1 (0.49) | SIK1SIK2SIK3ALDH1A1BMPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220402911-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES | GALAPAGOS NV (BE) | 2022-12-22 | — | — | US | disclosed |
| WO-2019238424-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES | GALAPAGOS NV (BE) | 2019-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220402911-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES | IL1A, TNF, IL6 | TAS1R3 1244/4885TAS1R1 1164/4885TAS1R2 1699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.