SCHEMBL2159497

SCHEMBL2159497

N[C@@H](CS)C(=O)OC(C=O)CO

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.40
SLC7A11 Q9UPY5 1/20 0.40
PAX8 Q06710 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3396294 0.78 PTGS1 (0.44) PTGS1SLC7A11
SCHEMBL4872186 0.78 PTGS1 (0.44) PTGS1SLC7A11
SCHEMBL736616 0.75 USP2 (0.39) PTGS1SLC7A11PAX8
SCHEMBL2159077 0.74 PAX8 (0.36) PTGS1SLC7A11PAX8
SCHEMBL9384783 0.73 PTGS1 (0.48) PTGS1SLC7A11
SCHEMBL5055049 0.72 PTGS1 (0.39) PTGS1SLC7A11
SCHEMBL1373431 0.71 PTGS1 (0.46) PTGS1SLC7A11
SCHEMBL1045518 0.71
SCHEMBL28984792 0.71 PTGS1 (0.46) PTGS1SLC7A11
SCHEMBL9674473 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150023941-A1 Compositions Comprising Sugar-Cysteine Products EAST WEST BANK 2015-01-22 US disclosed
US-20140348811-A1 COMPOSITIONS COMPRISING SUGAR-CYSTEINE PRODUCTS MAX INTERNATIONAL, LLC (US) 2014-11-27 US disclosed
US-8853170-B2 Compositions comprising sugar-cysteine products MAX INTERNATIONAL, LLC (US) 2014-10-07 US disclosed
WO-2013016636-A1 COMPOSITIONS COMPRISING SUGAR-CYSTEINE PRODUCTS MAX INTERNATIONAL, LLC (US) 2013-01-31 WO disclosed
WO-2011149835-A1 COMPOSITIONS AND BEVERAGES COMPRISING NUTRIENTS, VITAMINS, SUGARS, CYSTEINE, AND/OR SUGAR-CYSTEINE PRODUCTS MAX INTERNATIONAL, LLC (US) 2011-12-01 WO disclosed
US-20110287109-A1 Compositions And Beverages Comprising Nutrients, Vitamins, Sugars, Cysteine, And/Or Sugar-Cysteine Products MAX INTERNATIONAL, LLC (US) 2011-11-24 US disclosed
WO-2011094491-A1 COMPOSITIONS COMPRISING SUGAR-CYSTEINE PRODUCTS MAX INTERNATIONAL, LLC (US) 2011-08-04 WO disclosed
WO-2011094490-A1 METHODS OF PREPARING THIAZOLIDINES MAX INTERNATIONAL, LLC (US) 2011-08-04 WO disclosed
US-20110183927-A1 Compositions Comprising Sugar-Cysteine Products MAX INTERNATIONAL, LLC (US) 2011-07-28 US disclosed
US-20110184185-A1 Methods Of Preparing Thiazolidines MAX INTERNATIONAL, LLC (US) 2011-07-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110184185-A1 Methods Of Preparing Thiazolidines RPIA, DPYD, TXN PTGS1 2393/4885SLC7A11 469/4885PAX8 2269/4885
US-20150023941-A1 Compositions Comprising Sugar-Cysteine Products CBS, CTH, GCLC PTGS1 2672/4885SLC7A11 4/4885PAX8 3570/4885
US-20140348811-A1 COMPOSITIONS COMPRISING SUGAR-CYSTEINE PRODUCTS CBS, CTH, GCLC PTGS1 2672/4885SLC7A11 4/4885PAX8 3570/4885
US-20110183927-A1 Compositions Comprising Sugar-Cysteine Products CBS, CTH, GCLC PTGS1 2672/4885SLC7A11 4/4885PAX8 3570/4885
US-20110287109-A1 Compositions And Beverages Comprising Nutrients, Vitamins, Sugars, Cysteine, And/Or Sugar-Cysteine Products CBS, PROC, SLC7A11 PTGS1 1861/4885SLC7A11 3/4885PAX8 3426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.