Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 6/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21596477 | 0.96 | OPRK1 (0.40) | OPRK1NPSR1POLBTSHRHSD17B10 | |
| SCHEMBL28522607 | 0.89 | ALDH1A1 (0.46) | TSHRHSD17B10TP53CASP1ALDH1A1 | |
| SCHEMBL28533997 | 0.89 | ALDH1A1 (0.46) | OPRK1HSD17B10TP53ALDH1A1GABRA2 | |
| SCHEMBL2782609 | 0.86 | OPRK1 (0.48) | OPRK1NPSR1POLBTSHRHSD17B10 | |
| SCHEMBL9383978 | 0.86 | CASP1 (0.47) | TSHRCASP1ALDH1A1GABRA2MEN1 | |
| SCHEMBL3695889 | 0.74 | CYP1A2 (0.44) | OPRK1NPSR1POLBTSHRHSD17B10 | |
| SCHEMBL20472461 | 0.73 | ALDH1A1 (0.50) | OPRK1NPSR1POLBTSHRHSD17B10 | |
| SCHEMBL5864153 | 0.72 | OPRK1 (0.50) | OPRK1NPSR1POLBTSHRHSD17B10 | |
| SCHEMBL6715621 | 0.72 | KDM4E (0.49) | TSHRHSD17B10ALDH1A1GABRA2MEN1 | |
| SCHEMBL3582809 | 0.72 | CASP1 (0.49) | TSHRCASP1ALDH1A1MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810585-A1 | PROCESS FOR PREPARING TRICYCLIC COMPOUNDS | Bayer Aktiengesellschaft (DE) | 2021-04-28 | — | — | EP | disclosed |
| WO-2019243243-A1 | PROCESS FOR PREPARING TRICYCLIC COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 2019-12-26 | — | — | WO | disclosed |