SCHEMBL21596563

SCHEMBL21596563

COc1ccc(C(C)=COCCc2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.54
RAB9A P51151 4/20 0.54
GPR52 Q9Y2T5 1/20 0.50
MAPT P10636 3/20 0.46
LTA4H P09960 1/20 0.45
TDP1 Q9NUW8 2/20 0.44
GAA P10253 2/20 0.44
KMT2A Q03164 2/20 0.44
HTT P42858 1/20 0.44
L3MBTL1 Q9Y468 3/20 0.44
ALDH1A1 P00352 2/20 0.44
TAAR1 Q96RJ0 1/20 0.43
ACHE P22303 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
RECQL P46063 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21596632 0.88 ALDH1A1 (0.40) NPC1RAB9AGPR52TDP1KMT2A
SCHEMBL30118440 0.86 NPC1 (0.51) NPC1RAB9AMAPTLTA4HGAA
SCHEMBL21596605 0.85 GPR52 (0.46) NPC1RAB9AGPR52MAPTTDP1
SCHEMBL21596613 0.82 MAPT (0.51) NPC1RAB9AMAPTTDP1KMT2A
SCHEMBL21596612 0.82 MAPT (0.51) NPC1RAB9AMAPTTDP1KMT2A
SCHEMBL22443880 0.81 NPC1 (0.52) NPC1RAB9AGPR52MAPTLTA4H
SCHEMBL22125349 0.81 NPC1 (0.52) NPC1RAB9AGPR52MAPTLTA4H
SCHEMBL21596619 0.81 GPR52 (0.47) GPR52MAPTTDP1HTTACHE
SCHEMBL22125505 0.81 ALOX5 (0.49) NPC1RAB9AGPR52MAPTLTA4H
SCHEMBL23075169 0.80 NQO2 (0.47) RAB9AMAPTKMT2AALDH1A1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4711010-A2 PRO-PERFUME COMPOSITIONS Firmenich SA (CH) 2026-03-18 EP claimed
US-20250263631-A1 PRO-PERFUME COMPOSITIONS FIRMENICH SA (CH) 2025-08-21 US claimed
US-12325839-B2 Pro-perfume compositions FIRMENICH SA (CH) 2025-06-10 US claimed
US-20240050335-A1 A SYNERGISTIC PERFUMING COMPOSITION FIRMENICH & CIE (CH) 2024-02-15 US claimed
EP-4229165-A1 A SYNERGISTIC PERFUMING COMPOSITION Firmenich SA (CH) 2023-08-23 EP claimed
US-20230024269-A1 Pro-Perfume Compositions FIRMENICH SA (CH) 2023-01-26 US claimed
EP-4034073-A1 PRO-PERFUME COMPOSITIONS Firmenich SA (CH) 2022-08-03 EP claimed
CN-114727924-A Pro-fragrance compositions 弗门尼舍有限公司 2022-07-08 CN claimed
WO-2022129351-A1 A SYNERGISTIC PERFUMING COMPOSITION FIRMENICH SA (CH) 2022-06-23 WO claimed
WO-2021123144-A1 PRO-PERFUME COMPOSITIONS FIRMENICH SA (CH) 2021-06-24 WO claimed
US-12624309-B2 Enol ether properfume FIRMENICH SA (CH) 2026-05-12 US disclosed
WO-2026087780-A1 CORE-SHELL MICROCAPSULES FIRMENICH SA (CH) 2026-04-30 WO disclosed
EP-4724592-A2 PREPARATION OF TERPENOID COMPOUNDS Firmenich SA (CH) 2026-04-15 EP disclosed
EP-4724593-A2 POLYPEPTIDES FOR PREPARING TERPENOID COMPOUNDS Firmenich SA (CH) 2026-04-15 EP disclosed
EP-4514769-B1 MUSKY ODORANT FIRMENICH & CIE (CH) 2026-04-15 EP disclosed
US-20210115354-A1 ENOL ETHER PROPERFUME FIRMENICH SA (CH) 2021-04-22 US disclosed
WO-2021023647-A1 POLY(AMIDE-ESTER) MICROCAPSULES FIRMENICH SA (CH) 2021-02-11 WO disclosed
EP-3746420-A1 ENOL ETHER PROPERFUME Firmenich SA (CH) 2020-12-09 EP disclosed
WO-2020188079-A1 ENCAPSULATED PRO-PERFUME COMPOUNDS FIRMENICH SA (CH) 2020-09-24 WO disclosed
WO-2019243501-A1 ENOL ETHER PROPERFUME FIRMENICH SA (CH) 2019-12-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210115354-A1 ENOL ETHER PROPERFUME CYP2E1, ACADM, ALDH5A1 NPC1 1806/4885RAB9A 4541/4885GPR52 3638/4885
US-12624309-B2 Enol ether properfume CYP2E1, CBR1, ADH5 NPC1 1230/4885RAB9A 4382/4885GPR52 2023/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.