SCHEMBL21596596

SCHEMBL21596596

CC(C)=CCOC=Cc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.44
NDUFS8 O00217 1/20 0.42
COXFA4 O00483 1/20 0.42
NDUFAB1 O14561 1/20 0.42
NDUFA1 O15239 1/20 0.42
NDUFS4 O43181 1/20 0.42
NDUFB5 O43674 1/20 0.42
NDUFB3 O43676 1/20 0.42
NDUFC1 O43677 1/20 0.42
NDUFA2 O43678 1/20 0.42
NDUFS5 O43920 1/20 0.42
NDUFS7 O75251 1/20 0.42
NDUFS2 O75306 1/20 0.42
NDUFS6 O75380 1/20 0.42
NDUFB1 O75438 1/20 0.42
NDUFS3 O75489 1/20 0.42
NDUFB6 O95139 1/20 0.42
NDUFA3 O95167 1/20 0.42
NDUFB4 O95168 1/20 0.42
NDUFB8 O95169 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23244035 1.00 MAOB (0.44) MAOBNDUFS8COXFA4NDUFAB1NDUFA1
SCHEMBL20454554 0.76 IDO1 (0.46) MAOBIDO1RELATRPA1
SCHEMBL386809 0.75 MEN1 (0.49) MAOBIDO1RELATRPA1ALDH1A1
Methyl Alcohol SCHEMBL27549978 0.75 RELA (0.50) MAOBGLATDP1RELATRPA1
SCHEMBL7770634 0.75 MEN1 (0.49) MAOBIDO1RELATRPA1ALDH1A1
Benzene SCHEMBL28121960 0.74 RELA (0.53) MAOBIDO1ALOX15RELATRPA1
SCHEMBL17836905 0.74 RELA (0.53) MAOBIDO1ALOX15RELATRPA1
SCHEMBL60042 0.74 RELA (0.53) MAOBIDO1ALOX15RELATRPA1
SCHEMBL902965 0.74 MAOB (0.44) MAOBGLATDP1IDO1PPARG
SCHEMBL21596607 0.74 ALOX15 (0.47) TDP1PPARGPPARAALOX15ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111936457-B Enol ether pro-fragrances 弗门尼舍有限公司 2025-02-25 CN claimed
US-20230257678-A1 ENOL ETHER PROPERFUME FIRMENICH SA (CH) 2023-08-17 US claimed
EP-3746420-B1 ENOL ETHER PROPERFUME FIRMENICH & CIE (CH) 2023-08-16 EP claimed
US-20210115354-A1 ENOL ETHER PROPERFUME FIRMENICH SA (CH) 2021-04-22 US claimed
EP-3746420-A1 ENOL ETHER PROPERFUME Firmenich SA (CH) 2020-12-09 EP claimed
CN-111936457-A Enol ether pro-fragrances 弗门尼舍有限公司 2020-11-13 CN claimed
WO-2019243501-A1 ENOL ETHER PROPERFUME FIRMENICH SA (CH) 2019-12-26 WO claimed
CN-111936457-B Enol ether pro-fragrances 弗门尼舍有限公司 2025-02-25 CN disclosed
US-20230257678-A1 ENOL ETHER PROPERFUME FIRMENICH SA (CH) 2023-08-17 US disclosed
EP-3746420-B1 ENOL ETHER PROPERFUME FIRMENICH & CIE (CH) 2023-08-16 EP disclosed
US-11667869-B2 Enol ether pro perfume FIRMENICH SA (CH) 2023-06-06 US disclosed
US-20210115354-A1 ENOL ETHER PROPERFUME FIRMENICH SA (CH) 2021-04-22 US disclosed
CN-111936457-A Enol ether pro-fragrances 弗门尼舍有限公司 2020-11-13 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667869-B2 Enol ether pro perfume CYP2E1, ACADM, PEF1 MAOB 689/4885NDUFS8 56/4885COXFA4 10/4885
US-20230257678-A1 ENOL ETHER PROPERFUME CYP2E1, ADH5, ECI1 MAOB 325/4885NDUFS8 42/4885COXFA4 14/4885
US-20210115354-A1 ENOL ETHER PROPERFUME CYP2E1, ACADM, ALDH5A1 MAOB 627/4885NDUFS8 47/4885COXFA4 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.