Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.32 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 4/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21596920 | 0.76 | PIK3CD (0.43) | BRD4PIM1 | |
| SCHEMBL21596858 | 0.76 | BRD4 (0.41) | BRD4LTA4HHPGDSCCNCCDK8 | |
| SCHEMBL21596913 | 0.74 | CFTR (0.35) | BRD4CSNK1A1CSNK1DCSNK1E | |
| SCHEMBL21596921 | 0.73 | PIK3CD (0.47) | RET | |
| SCHEMBL17531762 | 0.72 | MEN1 (0.48) | BRD4LTA4HHPGDSCCNCCDK8 | |
| SCHEMBL722557 | 0.70 | LTA4H (0.64) | BRD4LTA4HHPGDSCCNCCDK8 | |
| SCHEMBL31734572 | 0.70 | DYRK1A (0.50) | LTA4HHPGDSS1PR1 | |
| SCHEMBL224239 | 0.69 | LTA4H (0.55) | LTA4HHPGDSKDRHDAC4CHRNA7 | |
| SCHEMBL26260185 | 0.69 | LTA4H (0.55) | BRD4LTA4HHPGDSCCNCCDK8 | |
| SCHEMBL15922137 | 0.69 | KMT2A (0.41) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810602-A1 | COMPOUNDS | CTXT Pty Limited (AU) | 2021-04-28 | — | — | EP | disclosed |
| WO-2019243491-A1 | COMPOUNDS | CTXT PTY LIMITED (AU) | 2019-12-26 | — | — | WO | disclosed |