Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21596936 | 0.87 | ALDH1A1 (0.33) | CA4HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL21596914 | 0.84 | MAPT (0.38) | ALDH1A1MAPK1 | |
| SCHEMBL21596845 | 0.78 | KAT7 (0.36) | — | |
| SCHEMBL21596930 | 0.73 | NQO2 (0.41) | CA4ALDH1A1TSHR | |
| SCHEMBL21596910 | 0.69 | CA4 (0.30) | CA4 | |
| SCHEMBL21596927 | 0.69 | FYN (0.41) | ALDH1A1TSHR | |
| SCHEMBL21596934 | 0.69 | ALDH1A1 (0.34) | CA4ALDH1A1 | |
| SCHEMBL31432799 | 0.68 | PTGS2 (0.63) | HTR2AHTR2CHTR2BPTGS2 | |
| SCHEMBL22016200 | 0.68 | PTGS2 (0.42) | HTR2AHTR2CHTR2BALDH1A1PTGS2 | |
| SCHEMBL22017083 | 0.67 | PTGS2 (0.45) | HTR2AHTR2CHTR2BALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810602-A1 | COMPOUNDS | CTXT Pty Limited (AU) | 2021-04-28 | — | — | EP | disclosed |
| WO-2019243491-A1 | COMPOUNDS | CTXT PTY LIMITED (AU) | 2019-12-26 | — | — | WO | disclosed |