Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 2/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | PDE6D | O43924 | 1/20 | 0.30 |
| ▸ | PDE6A | P16499 | 1/20 | 0.30 |
| ▸ | PDE6G | P18545 | 1/20 | 0.30 |
| ▸ | PDE6B | P35913 | 1/20 | 0.30 |
| ▸ | PDE6C | P51160 | 1/20 | 0.30 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21596846 | 0.78 | LTB4R (0.34) | ALDH1A1KDM4EHPGDCSF1RPDE2A | |
| SCHEMBL21596930 | 0.75 | NQO2 (0.41) | ALDH1A1KDM4EPOLBCA4 | |
| SCHEMBL21596910 | 0.73 | CA4 (0.30) | CA4 | |
| SCHEMBL21596936 | 0.72 | ALDH1A1 (0.33) | ALDH1A1POLBCA4 | |
| SCHEMBL21596927 | 0.71 | FYN (0.41) | ALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL21596916 | 0.69 | MLYCD (0.32) | ALDH1A1CA4 | |
| SCHEMBL21596932 | 0.68 | DCPS (0.51) | ALDH1A1KDM4EHPGD | |
| SCHEMBL14183056 | 0.68 | MEN1 (0.40) | ALDH1A1KDM4EPDE2APDE10APOLB | |
| SCHEMBL21596914 | 0.68 | MAPT (0.38) | ALDH1A1KDM4EGBA1HPGDCYP3A4 | |
| SCHEMBL23641248 | 0.67 | PIK3CA (0.38) | ALDH1A1CSF1RPDE2APDE10APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810602-A1 | COMPOUNDS | CTXT Pty Limited (AU) | 2021-04-28 | — | — | EP | disclosed |
| WO-2019243491-A1 | COMPOUNDS | CTXT PTY LIMITED (AU) | 2019-12-26 | — | — | WO | disclosed |