Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21596940 | 0.79 | ENPP2 (0.45) | KMT2AMEN1LMNAHTTGFER | |
| SCHEMBL2144895 | 0.79 | BACE1 (0.42) | KMT2AMEN1ACHEHTTRAB9A | |
| SCHEMBL8947000 | 0.75 | ACHE (0.43) | KMT2AMEN1LMNAHTR1AACHE | |
| SCHEMBL21596920 | 0.72 | PIK3CD (0.43) | KMT2AMEN1LMNAHTTDYRK1A | |
| SCHEMBL21596938 | 0.71 | LMNA (0.37) | LMNAMAOADYRK1AALDH1A1 | |
| Hydrochloric Acid SCHEMBL6648426 | 0.71 | RAB9A (0.46) | KMT2ALMNACHRM2ADRA2AADORA3 | |
| SCHEMBL21596921 | 0.69 | PIK3CD (0.47) | KMT2AMEN1LMNANPC1RAB9A | |
| SCHEMBL21596918 | 0.69 | BRD4 (0.39) | KDR | |
| SCHEMBL11198521 | 0.69 | KMT2A (0.50) | KMT2AMEN1F2LMNACHRM2 | |
| SCHEMBL15834740 | 0.68 | LMNA (0.38) | LMNAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2934538-A1 | FACTOR IXA INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2015-10-28 | — | — | EP | disclosed |
| WO-2014120346-A1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2014-08-07 | — | — | WO | disclosed |