Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.36 |
| ▸ | MPL | P40238 | 2/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | RBP4 | P02753 | 1/20 | 0.32 |
| ▸ | C1R | P00736 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4367263 | 0.76 | ACHE (0.39) | — | |
| SCHEMBL21596942 | 0.72 | BACE1 (0.40) | BRD4BACE1AXL | |
| SCHEMBL21596915 | 0.72 | PARP1 (0.41) | — | |
| SCHEMBL21609072 | 0.71 | KDR (0.50) | HRH4EPHX2KITKDRFLT3 | |
| SCHEMBL11285561 | 0.68 | EPHX2 (0.52) | BACE1EPHX2MPLKITKDR | |
| SCHEMBL11159666 | 0.68 | NCF1 (0.44) | BACE1MPLAXLALDH1A1TDP1 | |
| SCHEMBL22805659 | 0.68 | DHFR (0.55) | — | |
| SCHEMBL21596932 | 0.68 | DCPS (0.51) | ALDH1A1TDP1 | |
| SCHEMBL18312242 | 0.68 | PI4KA (0.44) | BACE1MPLALDH1A1 | |
| SCHEMBL30237719 | 0.68 | BACE1 (0.45) | HRH4BACE1EPHX2MPLC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810602-A1 | COMPOUNDS | CTXT Pty Limited (AU) | 2021-04-28 | — | — | EP | disclosed |
| WO-2019243491-A1 | COMPOUNDS | CTXT PTY LIMITED (AU) | 2019-12-26 | — | — | WO | disclosed |