Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | KCNA2 | P16389 | 1/20 | 0.31 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21596869 | 0.75 | LMNA (0.38) | LMNAKDM4EALDH1A1GAAHPGD | |
| SCHEMBL21596938 | 0.73 | LMNA (0.37) | LMNAALDH1A1 | |
| SCHEMBL9505644 | 0.69 | ALDH1A1 (0.43) | LMNAKDM4EALDH1A1GAAHPGD | |
| SCHEMBL21596919 | 0.68 | TYMS (0.32) | KDM4EALDH1A1TYMS | |
| SCHEMBL21596923 | 0.67 | ELANE (0.35) | LMNAKDM4EALDH1A1TYMS | |
| SCHEMBL10793829 | 0.67 | ALDH1A1 (0.41) | LMNAKDM4EALDH1A1GAAHPGD | |
| SCHEMBL29589613 | 0.65 | ALDH1A1 (0.48) | LMNAKDM4EALDH1A1GAAHPGD | |
| SCHEMBL27309614 | 0.65 | ALDH1A1 (0.48) | LMNAKDM4EALDH1A1GAAHPGD | |
| SCHEMBL3194453 | 0.65 | ALDH1A1 (0.40) | LMNAKDM4EALDH1A1GAAHPGD | |
| SCHEMBL21596925 | 0.64 | DYRK1A (0.44) | LMNAKDM4EALDH1A1HPGDTYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810602-A1 | COMPOUNDS | CTXT Pty Limited (AU) | 2021-04-28 | — | — | EP | disclosed |
| WO-2019243491-A1 | COMPOUNDS | CTXT PTY LIMITED (AU) | 2019-12-26 | — | — | WO | disclosed |