Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | BAD | Q92934 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 3/20 | 0.31 |
| ▸ | NOS3 | P29474 | 2/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | KAT7 | O95251 | 1/20 | 0.30 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947000 | 0.75 | ACHE (0.43) | LMNATP53CA2ALDH1A1 | |
| SCHEMBL21596776 | 0.74 | LMNA (0.40) | LMNATP53MAOADYRK1ACA2 | |
| SCHEMBL21596945 | 0.73 | LMNA (0.35) | LMNAALDH1A1 | |
| SCHEMBL21596936 | 0.72 | ALDH1A1 (0.33) | LMNAALDH1A1KAT7KAT6A | |
| SCHEMBL21596940 | 0.72 | ENPP2 (0.45) | LMNAALDH1A1 | |
| SCHEMBL15922137 | 0.71 | KMT2A (0.41) | LMNAMAOADYRK1AALDH1A1 | |
| SCHEMBL13036359 | 0.70 | KCNJ1 (0.49) | LMNATP53ALDH1A1 | |
| SCHEMBL2144895 | 0.68 | BACE1 (0.42) | ALDH1A1 | |
| SCHEMBL13765046 | 0.68 | MAPT (0.51) | LMNATP53ALDH1A1 | |
| SCHEMBL15732195 | 0.67 | MAOA (0.45) | LMNATP53MAOADYRK1ASLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810602-A1 | COMPOUNDS | CTXT Pty Limited (AU) | 2021-04-28 | — | — | EP | disclosed |
| WO-2019243491-A1 | COMPOUNDS | CTXT PTY LIMITED (AU) | 2019-12-26 | — | — | WO | disclosed |