Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21597978 | 0.78 | POLB (0.40) | ALDH1A1SMN1; SMN2HTTLMNATSHR | |
| SCHEMBL361383 | 0.74 | LMNA (0.66) | NPC1RAB9AALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL2841534 | 0.73 | CES2 (0.45) | ALDH1A1HTTLMNAHPGDTSHR | |
| SCHEMBL8218800 | 0.72 | LMNA (0.63) | NPC1RAB9AALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL6449983 | 0.72 | LMNA (0.42) | RAB9AALDH1A1SMN1; SMN2TP53HTT | |
| SCHEMBL6449984 | 0.72 | LMNA (0.42) | RAB9AALDH1A1SMN1; SMN2TP53HTT | |
| SCHEMBL8585753 | 0.71 | ALDH1A1 (0.44) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL9671485 | 0.70 | LMNA (0.59) | NPC1RAB9AALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL26009141 | 0.70 | MTNR1B (0.59) | NPC1RAB9AALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL27461061 | 0.69 | HCAR2 (0.51) | NPC1RAB9AALDH1A1TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243576-A1 | GLUCOSE-SENSITIVE PEPTIDE HORMONES | GUBRA APS (DK) | 2019-12-26 | — | — | WO | disclosed |