Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 8/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 7/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 7/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 7/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 7/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 7/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21600743 | 0.88 | CYP3A4 (0.37) | ACHEALDH1A1CYP3A4LMNATSHR | |
| SCHEMBL30662156 | 0.88 | CYP3A4 (0.37) | ACHEALDH1A1CYP3A4LMNATSHR | |
| SCHEMBL23142584 | 0.87 | MCOLN3 (0.35) | ACHEALDH1A1POLBLMNAHTR2A | |
| SCHEMBL21600717 | 0.86 | L3MBTL1 (0.38) | ALDH1A1LMNATSHRMAPK1MEN1 | |
| SCHEMBL21600725 | 0.86 | DDB1 (0.41) | SLC6A3ALDH1A1CYP3A4HTR2ASMN1; SMN2 | |
| SCHEMBL24246859 | 0.86 | GAA (0.38) | ALDH1A1CYP3A4LMNATSHRSMN1; SMN2 | |
| SCHEMBL21600709 | 0.86 | PSIP1 (0.36) | ACHEALDH1A1LMNAHTR2ASMN1; SMN2 | |
| SCHEMBL29457734 | 0.85 | CA2 (0.42) | SLC6A3ALDH1A1CYP3A4LMNAHTR2A | |
| SCHEMBL21600740 | 0.85 | MMP2 (0.37) | ALDH1A1HTR2AMEN1KMT2AMMP2 | |
| SCHEMBL24246845 | 0.84 | PTGS2 (0.36) | ALDH1A1CYP3A4POLBLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11247977-B2 | Compound and use thereof in synthesis of brivaracetam intermediate and crude drug | FUJIAN HAIXI PHARMACEUTICALS CO., LTD. (CN) | 2022-02-15 | — | — | US | disclosed |
| US-11247977-B2 | Compound and use thereof in synthesis of brivaracetam intermediate and crude drug | FUJIAN HAIXI PHARMACEUTICALS CO., LTD. (CN) | 2022-02-15 | — | — | US | disclosed |
| EP-3798211-A1 | COMPOUND AND USE THEREOF IN SYNTHESIS OF BRIVARACETAM INTERMEDIATE AND CRUDE DRUG | Fujian Haixi Pharmaceuticals Co., Ltd (CN) | 2021-03-31 | — | — | EP | disclosed |
| WO-2019242692-A1 | COMPOUND AND USE THEREOF IN SYNTHESIS OF BRIVARACETAM INTERMEDIATE AND CRUDE DRUG | 福建海西新药创制有限公司 | 2019-12-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11247977-B2 | Compound and use thereof in synthesis of brivaracetam intermediate and crude drug | CYP3A43, POR, CYP2C19 | PSEN1 2812/4885PSEN2 2365/4885APH1B 2429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.