Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.49 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.49 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL594361 | 0.87 | ALDH1A1 (0.60) | FGFR1L3MBTL1ALDH1A1HTTTXNRD1 | |
| SCHEMBL19911399 | 0.80 | FGFR1 (0.60) | FGFR1L3MBTL1ALDH1A1HTTTXNRD1 | |
| SCHEMBL8337275 | 0.80 | FGFR1 (0.60) | FGFR1L3MBTL1ALDH1A1HTTTXNRD1 | |
| SCHEMBL8425553 | 0.80 | FGFR1 (0.60) | FGFR1L3MBTL1ALDH1A1HTTTXNRD1 | |
| SCHEMBL1489409 | 0.80 | L3MBTL1 (0.66) | FGFR1L3MBTL1ALDH1A1HTTTXNRD1 | |
| Hydrochloric Acid SCHEMBL2422409 | 0.79 | FGFR1 (0.58) | FGFR1L3MBTL1ALDH1A1HTTTXNRD1 | |
| SCHEMBL19911375 | 0.78 | FGFR1 (0.57) | FGFR1L3MBTL1ALDH1A1HTTTXNRD1 | |
| SCHEMBL19911374 | 0.78 | FGFR1 (0.57) | FGFR1L3MBTL1ALDH1A1HTTTXNRD1 | |
| SCHEMBL7036153 | 0.76 | FGFR1 (0.56) | FGFR1L3MBTL1ALDH1A1HTTTXNRD1 | |
| SCHEMBL19911390 | 0.76 | FGFR1 (0.56) | FGFR1L3MBTL1ALDH1A1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985771-B2 | Skin disorders; aging resistance | MONSANTO TECHNOLOGY LLC (US) | 2011-07-26 | — | — | US | disclosed |
| EP-1660080-A1 | FURANONE DERIVATIVES | Galileo Pharmaceuticals, Inc. (US) | 2006-05-31 | — | — | EP | disclosed |
| EP-1478634-A4 | FURANONE DERIVATIVES | GALILEO PHARMACEUTICALS INC (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2005016340-A1 | FURANONE DERIVATIVES | GALILEO PHARMACEUTICALS, INC. (US) | 2005-02-24 | — | — | WO | disclosed |
| EP-1478634-A1 | FURANONE DERIVATIVES | Galileo Pharmaceuticals, Inc. (US) | 2004-11-24 | — | — | EP | disclosed |
| US-20040029812-A1 | Furanone derivatives | MONSANTO TECHNOLOGY LLC | 2004-02-12 | — | — | US | disclosed |
| US-6667330-B2 | Cytoprotective; neuroinflammation and neurodegenerative disorders; oxidative stress related conditions | GALILEO PHARMACEUTICALS, INC. | 2003-12-23 | — | — | US | disclosed |
| US-20030176361-A1 | Furanone derivatives | MONSANTO TECHNOLOGY LLC | 2003-09-18 | — | — | US | disclosed |
| WO-2003064403-A1 | FURANONE DERIVATIVES | GALILEO LABORATORIES, INC. (US) | 2003-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176361-A1 | Furanone derivatives | HSPA9, HSF1, IL1B | FGFR1 1152/4885L3MBTL1 4751/4885ALDH1A1 903/4885 |
| US-20040029812-A1 | Furanone derivatives | TNF, PPIF, NOX5 | FGFR1 129/4885L3MBTL1 4884/4885ALDH1A1 944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.