Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9692360 | 0.86 | TSHR (0.51) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL21607508 | 0.81 | BACE1 (0.51) | NPC1RAB9ACES2CES1SMN1; SMN2 | |
| SCHEMBL19214443 | 0.81 | BACE1 (0.51) | NPC1RAB9ACES2CES1SMN1; SMN2 | |
| SCHEMBL20712075 | 0.80 | POLB (0.50) | ALDH1A1TSHRMAPK1CYP2D6SMN1; SMN2 | |
| SCHEMBL3096445 | 0.80 | POLB (0.50) | ALDH1A1TSHRMAPK1CYP2D6SMN1; SMN2 | |
| SCHEMBL3096440 | 0.80 | POLB (0.50) | ALDH1A1TSHRMAPK1CYP2D6SMN1; SMN2 | |
| SCHEMBL2747635 | 0.80 | POLB (0.50) | ALDH1A1TSHRMAPK1CYP2D6SMN1; SMN2 | |
| SCHEMBL21607170 | 0.78 | ALDH1A1 (0.46) | ALDH1A1RAB9ATSHRMAPK1HSD17B10 | |
| SCHEMBL7939239 | 0.75 | NR3C1 (0.54) | KDM4EALDH1A1GAARAB9ATSHR | |
| SCHEMBL7947759 | 0.75 | NR3C1 (0.54) | KDM4EALDH1A1GAARAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243576-A1 | GLUCOSE-SENSITIVE PEPTIDE HORMONES | GUBRA APS (DK) | 2019-12-26 | — | — | WO | disclosed |