Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | QDPR | P09417 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947759 | 1.00 | NR3C1 (0.54) | NR3C1CA2ALOX5PTPN1PPARG | |
| SCHEMBL7945646 | 0.86 | HSD17B2 (0.51) | NR3C1CA2ALOX5PTPN1PPARG | |
| SCHEMBL7948495 | 0.86 | HSD17B2 (0.51) | NR3C1CA2ALOX5PTPN1PPARG | |
| SCHEMBL29663534 | 0.80 | NR3C1 (0.66) | NR3C1CA2ALOX5PTPN1PPARG | |
| SCHEMBL11913924 | 0.80 | NR3C1 (0.66) | NR3C1CA2ALOX5PTPN1PPARG | |
| SCHEMBL19214443 | 0.76 | BACE1 (0.51) | CA2KMT2ARAB9A | |
| SCHEMBL21607508 | 0.76 | BACE1 (0.51) | CA2KMT2ARAB9A | |
| SCHEMBL7950800 | 0.75 | ALDH1A1 (0.47) | GAAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7939252 | 0.75 | ALDH1A1 (0.47) | GAAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL21607231 | 0.75 | KDM4E (0.48) | GAAKDM4EALDH1A1CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3159388-B2 | — | — | 2001-04-23 | — | — | JP | claimed |
| US-5371069-A | Organoleptic compositions | GIUAUDAN-ROURE CORPORATION (US) | 1994-12-06 | — | — | US | claimed |
| EP-0515622-B1 | ORGANOLEPTIC COMPOSITIONS | GIVAUDAN ROURE INT (CH) | 1994-07-20 | — | — | EP | claimed |
| EP-0515622-A1 | ORGANOLEPTIC COMPOSITIONS. | GIVAUDAN ROURE INT (CH) | 1992-12-02 | — | — | EP | claimed |
| US-5144048-A | Dicarboalkoxy dioxolane derivatives | L. GIVAUDAN & CIE, S.A. (CH) | 1992-09-01 | — | — | US | claimed |
| WO-1992010107-A1 | ORGANOLEPTIC COMPOSITIONS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1992-06-25 | — | — | WO | claimed |
| US-5371069-A | Organoleptic compositions | GIUAUDAN-ROURE CORPORATION (US) | 1994-12-06 | — | — | US | disclosed |